BRAF Mutation (V600E) Prevalence in Mexican Patients Diagnosed with Melanoma

BRAF Mutation (V600E) Prevalence in Mexican Patients Diagnosed with Melanoma

Background: B-Raf is a serine/threonine protein kinase activating the MAP kinase/ERK-signaling pathway. It has been shown that 50% of melanomas harbor activating BRAF mutations, with over 90% being the V600E mutation. Objective: The goal of this research was to determine the prevalence of the BRAF V...

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Bibliographic Details
Main Authors: Priscilla Denise Zepeda-Lopez, Julio Cesar Salas-Alanis, Sonia Toussaint-Caire, Daniela Gutierrez-Mendoza, Elisa Vega-Memije, Saúl Lino Silva, Oscar Raul Fajardo-Ramírez, Gregorio Alcazar, María Guadalupe Moreno-Treviño, Hugo Alberto Barrera Saldaña
Format: Article
Language:English
Published: Karger Publishers 2016-04-01
Series:Case Reports in Oncology
Subjects:
Mexican patients
Melanoma
BRAF
V600E mutation
Online Access:http://www.karger.com/Article/FullText/445939

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