Clinical evaluation of non-invasive prenatal screening for the detection of fetal genome-wide copy number variants
Abstract Objective This study explores and discusses the possible factors affecting the positive predictive value (PPV) of non-invasive prenatal screening (NIPS) for the detection of fetal copy number variants (CNVs) in pregnant women. Methods NIPS was performed for 50,972 pregnant women and 212 cas...
Main Authors: | Wenli Wang, Fengying Lu, Bin Zhang, Qin Zhou, Yingping Chen, Bin Yu |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-07-01
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Series: | Orphanet Journal of Rare Diseases |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13023-022-02406-6 |
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