The relationship between cardiovascular risk factors and the site and extent of coronary artery stenosis during angiography

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Main Authors: Zand Parsa AF, Ziai H, Fallahi B
Format: Article
Language:fas
Published: Tehran University of Medical Sciences 2010-06-01
Series:Tehran University Medical Journal
Subjects:
Online Access:http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/15816.pdf&manuscript_id=15816
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author Zand Parsa AF
Ziai H
Fallahi B
author_facet Zand Parsa AF
Ziai H
Fallahi B
author_sort Zand Parsa AF
collection DOAJ
description "n Normal 0 false false false EN-US X-NONE AR-SA MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:Arial; mso-bidi-theme-font:minor-bidi;} Background: Coronary Artery Disease (CAD) is one of the leading causes of mortality and morbidity all over the world. One of the most important predictors of the outcome of the coronary stenosis is the site of the lesions i.e. Proximal versus nonproximal lesions. This study designed to evaluate the relationship between CAD risk factors and site of stenosis."n"nMethods: In this case- control study in the patients undergone coronary angiography (CAG) in Imam Khomeini Hospital, Tehran, Iran a total of 125 CAD patients with proximal lesion in CAG enrolled the study as case group and equal sex and age matched number of patients with non proximal lesion selected as control group. Two groups were compared based on presence or absence of DM, hypertension, hyper cholestrolemia, hypertriglyceridemia and cigarette smoking."n"nResults: Relative frequency of DM was 33.6% and 10.4% in case and control group respectively (p< 0.0001). Relative frequency in two groups were 33.6 vs 28.8% For HTN (p= 0.41), 30.4% vs 29.6% for hyper cholestrolemia (p= 0.89), 19.2% vs 16.8% for hypertriglyceridemia (p= 0.062) and 28.8 vs 39.2 for C/S (p= 0.08). Multivessle disease was significantly more prevalent in diabetics compared with non diabetic patients 89.1% vs 61% (p< 0.0001), no relationship was seen with HTN (p= 0.41), Hyper cholest-rolemia (p= 0.052) hypertriglyceridemia (p= 0.38) and cigarette smoking (p= 0.375)."n"nConclusion: Proximal involvement of coronary arteries and multivessle disease in CAD patients is related to history of DM but not to history of hypertension, hypercholestrolemia, hypertriglyceridemia and cigarette smoking.
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spelling doaj.art-761100a92a124afca0d2e4fe469226aa2022-12-21T19:31:54ZfasTehran University of Medical SciencesTehran University Medical Journal1683-17641735-73222010-06-01683182187The relationship between cardiovascular risk factors and the site and extent of coronary artery stenosis during angiographyZand Parsa AFZiai HFallahi B"n Normal 0 false false false EN-US X-NONE AR-SA MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:Arial; mso-bidi-theme-font:minor-bidi;} Background: Coronary Artery Disease (CAD) is one of the leading causes of mortality and morbidity all over the world. One of the most important predictors of the outcome of the coronary stenosis is the site of the lesions i.e. Proximal versus nonproximal lesions. This study designed to evaluate the relationship between CAD risk factors and site of stenosis."n"nMethods: In this case- control study in the patients undergone coronary angiography (CAG) in Imam Khomeini Hospital, Tehran, Iran a total of 125 CAD patients with proximal lesion in CAG enrolled the study as case group and equal sex and age matched number of patients with non proximal lesion selected as control group. Two groups were compared based on presence or absence of DM, hypertension, hyper cholestrolemia, hypertriglyceridemia and cigarette smoking."n"nResults: Relative frequency of DM was 33.6% and 10.4% in case and control group respectively (p< 0.0001). Relative frequency in two groups were 33.6 vs 28.8% For HTN (p= 0.41), 30.4% vs 29.6% for hyper cholestrolemia (p= 0.89), 19.2% vs 16.8% for hypertriglyceridemia (p= 0.062) and 28.8 vs 39.2 for C/S (p= 0.08). Multivessle disease was significantly more prevalent in diabetics compared with non diabetic patients 89.1% vs 61% (p< 0.0001), no relationship was seen with HTN (p= 0.41), Hyper cholest-rolemia (p= 0.052) hypertriglyceridemia (p= 0.38) and cigarette smoking (p= 0.375)."n"nConclusion: Proximal involvement of coronary arteries and multivessle disease in CAD patients is related to history of DM but not to history of hypertension, hypercholestrolemia, hypertriglyceridemia and cigarette smoking.http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/15816.pdf&manuscript_id=15816Coronary angiographycoronary artery diseaseproximaldistallesionscardiacrisk factors
spellingShingle Zand Parsa AF
Ziai H
Fallahi B
The relationship between cardiovascular risk factors and the site and extent of coronary artery stenosis during angiography
Tehran University Medical Journal
Coronary angiography
coronary artery disease
proximal
distal
lesions
cardiac
risk factors
title The relationship between cardiovascular risk factors and the site and extent of coronary artery stenosis during angiography
title_full The relationship between cardiovascular risk factors and the site and extent of coronary artery stenosis during angiography
title_fullStr The relationship between cardiovascular risk factors and the site and extent of coronary artery stenosis during angiography
title_full_unstemmed The relationship between cardiovascular risk factors and the site and extent of coronary artery stenosis during angiography
title_short The relationship between cardiovascular risk factors and the site and extent of coronary artery stenosis during angiography
title_sort relationship between cardiovascular risk factors and the site and extent of coronary artery stenosis during angiography
topic Coronary angiography
coronary artery disease
proximal
distal
lesions
cardiac
risk factors
url http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/15816.pdf&manuscript_id=15816
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