Solution Self-Assembly of Coil-Crystalline Diblock Copolypeptoids Bearing Alkyl Side Chains
Polypeptoids, a class of synthetic peptidomimetic polymers, have attracted increasing attention due to their potential for biotechnological applications, such as drug/gene delivery, sensing and molecular recognition. Recent investigations on the solution self-assembly of amphiphilic block copolypept...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-09-01
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| Series: | Polymers |
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| Online Access: | https://www.mdpi.com/2073-4360/13/18/3131 |
| _version_ | 1797517426595725312 |
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| author | Naisheng Jiang Donghui Zhang |
| author_facet | Naisheng Jiang Donghui Zhang |
| author_sort | Naisheng Jiang |
| collection | DOAJ |
| description | Polypeptoids, a class of synthetic peptidomimetic polymers, have attracted increasing attention due to their potential for biotechnological applications, such as drug/gene delivery, sensing and molecular recognition. Recent investigations on the solution self-assembly of amphiphilic block copolypeptoids highlighted their capability to form a variety of nanostructures with tailorable morphologies and functionalities. Here, we review our recent findings on the solutions self-assembly of coil-crystalline diblock copolypeptoids bearing alkyl side chains. We highlight the solution self-assembly pathways of these polypeptoid block copolymers and show how molecular packing and crystallization of these building blocks affect the self-assembly behavior, resulting in one-dimensional (1D), two-dimensional (2D) and multidimensional hierarchical polymeric nanostructures in solution. |
| first_indexed | 2024-03-10T07:16:28Z |
| format | Article |
| id | doaj.art-7611607db04e464da5187b8468c851a1 |
| institution | Directory Open Access Journal |
| issn | 2073-4360 |
| language | English |
| last_indexed | 2024-03-10T07:16:28Z |
| publishDate | 2021-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Polymers |
| spelling | doaj.art-7611607db04e464da5187b8468c851a12023-11-22T14:56:36ZengMDPI AGPolymers2073-43602021-09-011318313110.3390/polym13183131Solution Self-Assembly of Coil-Crystalline Diblock Copolypeptoids Bearing Alkyl Side ChainsNaisheng Jiang0Donghui Zhang1School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, ChinaMacromolecular Studies Group, Department of Chemistry, Louisiana State University, Baton Rouge, LA 70803, USAPolypeptoids, a class of synthetic peptidomimetic polymers, have attracted increasing attention due to their potential for biotechnological applications, such as drug/gene delivery, sensing and molecular recognition. Recent investigations on the solution self-assembly of amphiphilic block copolypeptoids highlighted their capability to form a variety of nanostructures with tailorable morphologies and functionalities. Here, we review our recent findings on the solutions self-assembly of coil-crystalline diblock copolypeptoids bearing alkyl side chains. We highlight the solution self-assembly pathways of these polypeptoid block copolymers and show how molecular packing and crystallization of these building blocks affect the self-assembly behavior, resulting in one-dimensional (1D), two-dimensional (2D) and multidimensional hierarchical polymeric nanostructures in solution.https://www.mdpi.com/2073-4360/13/18/3131polypeptoidsdiblock copolymerscrystallizationsolution self-assembly |
| spellingShingle | Naisheng Jiang Donghui Zhang Solution Self-Assembly of Coil-Crystalline Diblock Copolypeptoids Bearing Alkyl Side Chains Polymers polypeptoids diblock copolymers crystallization solution self-assembly |
| title | Solution Self-Assembly of Coil-Crystalline Diblock Copolypeptoids Bearing Alkyl Side Chains |
| title_full | Solution Self-Assembly of Coil-Crystalline Diblock Copolypeptoids Bearing Alkyl Side Chains |
| title_fullStr | Solution Self-Assembly of Coil-Crystalline Diblock Copolypeptoids Bearing Alkyl Side Chains |
| title_full_unstemmed | Solution Self-Assembly of Coil-Crystalline Diblock Copolypeptoids Bearing Alkyl Side Chains |
| title_short | Solution Self-Assembly of Coil-Crystalline Diblock Copolypeptoids Bearing Alkyl Side Chains |
| title_sort | solution self assembly of coil crystalline diblock copolypeptoids bearing alkyl side chains |
| topic | polypeptoids diblock copolymers crystallization solution self-assembly |
| url | https://www.mdpi.com/2073-4360/13/18/3131 |
| work_keys_str_mv | AT naishengjiang solutionselfassemblyofcoilcrystallinediblockcopolypeptoidsbearingalkylsidechains AT donghuizhang solutionselfassemblyofcoilcrystallinediblockcopolypeptoidsbearingalkylsidechains |