Comparison of flexible, open with semi-rigid, closed annuloplasty-rings for mitral valve repair
Abstract Background Mitral regurgitation is a frequent valvular disease, with an increasing prevalence. We analysed the long-term outcomes of mitral valve repair procedures conducted over the last 10 years in our clinic using almost exclusively two different annuloplasty ring types. Methods A single...
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| Format: | Article |
| Language: | English |
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BMC
2021-03-01
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| Series: | Journal of Cardiothoracic Surgery |
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| Online Access: | https://doi.org/10.1186/s13019-021-01405-1 |
| _version_ | 1818416558809022464 |
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| author | Ayse Cetinkaya Maryam Waheed Karin Bramlage Oliver Johannes Liakopoulos Mohamed Zeriouh Stefan Hein Peter Bramlage Markus Schönburg Yeong-Hoon Choi Manfred Richter |
| author_facet | Ayse Cetinkaya Maryam Waheed Karin Bramlage Oliver Johannes Liakopoulos Mohamed Zeriouh Stefan Hein Peter Bramlage Markus Schönburg Yeong-Hoon Choi Manfred Richter |
| author_sort | Ayse Cetinkaya |
| collection | DOAJ |
| description | Abstract Background Mitral regurgitation is a frequent valvular disease, with an increasing prevalence. We analysed the long-term outcomes of mitral valve repair procedures conducted over the last 10 years in our clinic using almost exclusively two different annuloplasty ring types. Methods A single-centre, retrospective analysis of mitral valve surgeries conducted between January 2005 and December 2015 for patients undergoing first-line mitral valve repair with either open (Cosgrove) or closed (CE Physio / Physio II) annuloplasty (OA or CA, respectively) rings. Results In total, 1120 patient documentations were available of which 528 underwent OA and 592 patients CA. The median age of patients was 64.0 years and 41.1% were female. The majority of these patients underwent the procedure because of degenerative valve disease. Rates of successful repair were about 90%, 72 h procedural mortality was 0.6% and the rate of re-intervention was 0.6% within the first 30 days. Functional (mitral regurgitation, left ventricular ejection fraction, left ventricular end-diastolic and systolic diameter and New York Heart Association class) as well as hard outcomes were comparable. 77.7 and 74.4% of patients were alive at the 10-year follow-up in the OA and CA groups, respectively. Upon multivariable adjustment, the hazard ratio was 0.926 (95% CI: 0.642–1.3135; p = 0.681). Conclusions The functional outcome and survival rates up to 10 years after mitral valve repair were comparable using open and closed annuloplasty rings. Whether this means these rings are interchangeable or a carefully selection of the best-for-the-patient devices will be subject of future investigations. |
| first_indexed | 2024-12-14T11:52:48Z |
| format | Article |
| id | doaj.art-76155437deba4df3affe765da18aca3b |
| institution | Directory Open Access Journal |
| issn | 1749-8090 |
| language | English |
| last_indexed | 2024-12-14T11:52:48Z |
| publishDate | 2021-03-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Cardiothoracic Surgery |
| spelling | doaj.art-76155437deba4df3affe765da18aca3b2022-12-21T23:02:14ZengBMCJournal of Cardiothoracic Surgery1749-80902021-03-0116111110.1186/s13019-021-01405-1Comparison of flexible, open with semi-rigid, closed annuloplasty-rings for mitral valve repairAyse Cetinkaya0Maryam Waheed1Karin Bramlage2Oliver Johannes Liakopoulos3Mohamed Zeriouh4Stefan Hein5Peter Bramlage6Markus Schönburg7Yeong-Hoon Choi8Manfred Richter9Department of Cardiac Surgery, Kerckhoff-Heart Center Bad Nauheim, Campus of the University Hospital Giessen, Justus-Liebig Universiy GiessenDepartment of Cardiac Surgery, Kerckhoff-Heart Center Bad Nauheim, Campus of the University Hospital Giessen, Justus-Liebig Universiy GiessenInstitute for Pharmacology and Preventive MedicineDepartment of Cardiac Surgery, Kerckhoff-Heart Center Bad Nauheim, Campus of the University Hospital Giessen, Justus-Liebig Universiy GiessenDepartment of Cardiac Surgery, Kerckhoff-Heart Center Bad Nauheim, Campus of the University Hospital Giessen, Justus-Liebig Universiy GiessenDepartment of Cardiac Surgery, Kerckhoff-Heart Center Bad Nauheim, Campus of the University Hospital Giessen, Justus-Liebig Universiy GiessenInstitute for Pharmacology and Preventive MedicineDepartment of Cardiac Surgery, Kerckhoff-Heart Center Bad Nauheim, Campus of the University Hospital Giessen, Justus-Liebig Universiy GiessenDepartment of Cardiac Surgery, Kerckhoff-Heart Center Bad Nauheim, Campus of the University Hospital Giessen, Justus-Liebig Universiy GiessenDepartment of Cardiac Surgery, Kerckhoff-Heart Center Bad Nauheim, Campus of the University Hospital Giessen, Justus-Liebig Universiy GiessenAbstract Background Mitral regurgitation is a frequent valvular disease, with an increasing prevalence. We analysed the long-term outcomes of mitral valve repair procedures conducted over the last 10 years in our clinic using almost exclusively two different annuloplasty ring types. Methods A single-centre, retrospective analysis of mitral valve surgeries conducted between January 2005 and December 2015 for patients undergoing first-line mitral valve repair with either open (Cosgrove) or closed (CE Physio / Physio II) annuloplasty (OA or CA, respectively) rings. Results In total, 1120 patient documentations were available of which 528 underwent OA and 592 patients CA. The median age of patients was 64.0 years and 41.1% were female. The majority of these patients underwent the procedure because of degenerative valve disease. Rates of successful repair were about 90%, 72 h procedural mortality was 0.6% and the rate of re-intervention was 0.6% within the first 30 days. Functional (mitral regurgitation, left ventricular ejection fraction, left ventricular end-diastolic and systolic diameter and New York Heart Association class) as well as hard outcomes were comparable. 77.7 and 74.4% of patients were alive at the 10-year follow-up in the OA and CA groups, respectively. Upon multivariable adjustment, the hazard ratio was 0.926 (95% CI: 0.642–1.3135; p = 0.681). Conclusions The functional outcome and survival rates up to 10 years after mitral valve repair were comparable using open and closed annuloplasty rings. Whether this means these rings are interchangeable or a carefully selection of the best-for-the-patient devices will be subject of future investigations.https://doi.org/10.1186/s13019-021-01405-1Mitral valve repairMitral regurgitationAnnuloplastyOpen ringClosed ring |
| spellingShingle | Ayse Cetinkaya Maryam Waheed Karin Bramlage Oliver Johannes Liakopoulos Mohamed Zeriouh Stefan Hein Peter Bramlage Markus Schönburg Yeong-Hoon Choi Manfred Richter Comparison of flexible, open with semi-rigid, closed annuloplasty-rings for mitral valve repair Journal of Cardiothoracic Surgery Mitral valve repair Mitral regurgitation Annuloplasty Open ring Closed ring |
| title | Comparison of flexible, open with semi-rigid, closed annuloplasty-rings for mitral valve repair |
| title_full | Comparison of flexible, open with semi-rigid, closed annuloplasty-rings for mitral valve repair |
| title_fullStr | Comparison of flexible, open with semi-rigid, closed annuloplasty-rings for mitral valve repair |
| title_full_unstemmed | Comparison of flexible, open with semi-rigid, closed annuloplasty-rings for mitral valve repair |
| title_short | Comparison of flexible, open with semi-rigid, closed annuloplasty-rings for mitral valve repair |
| title_sort | comparison of flexible open with semi rigid closed annuloplasty rings for mitral valve repair |
| topic | Mitral valve repair Mitral regurgitation Annuloplasty Open ring Closed ring |
| url | https://doi.org/10.1186/s13019-021-01405-1 |
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