Functionalized Hemodialysis Polysulfone Membranes with Improved Hemocompatibility

The field of membrane materials is one of the most dynamic due to the continuously changing requirements regarding the selectivity and the upgradation of the materials developed with the constantly changing needs. Two membrane processes are essential at present, not for development, but for everyday...

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Main Authors: Elena Ruxandra Radu, Stefan Ioan Voicu
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Polymers
Subjects:
Online Access:https://www.mdpi.com/2073-4360/14/6/1130
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author Elena Ruxandra Radu
Stefan Ioan Voicu
author_facet Elena Ruxandra Radu
Stefan Ioan Voicu
author_sort Elena Ruxandra Radu
collection DOAJ
description The field of membrane materials is one of the most dynamic due to the continuously changing requirements regarding the selectivity and the upgradation of the materials developed with the constantly changing needs. Two membrane processes are essential at present, not for development, but for everyday life—desalination and hemodialysis. Hemodialysis has preserved life and increased life expectancy over the past 60–70 years for tens of millions of people with chronic kidney dysfunction. In addition to the challenges related to the efficiency and separative properties of the membranes, the biggest challenge remained and still remains the assurance of hemocompatibility—not affecting the blood during its recirculation outside the body for 4 h once every two days. This review presents the latest research carried out in the field of functionalization of polysulfone membranes (the most used polymer in the preparation of membranes for hemodialysis) with the purpose of increasing the hemocompatibility and efficiency of the separation process itself with a decreasing impact on the body.
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spelling doaj.art-7616dd05c4f54f03b1e166587e0313fd2023-11-30T22:02:56ZengMDPI AGPolymers2073-43602022-03-01146113010.3390/polym14061130Functionalized Hemodialysis Polysulfone Membranes with Improved HemocompatibilityElena Ruxandra Radu0Stefan Ioan Voicu1Advanced Polymer Materials Group, University Politehnica of Bucharest, 1-7 Gh. Polizu Street, 011061 Bucharest, RomaniaAdvanced Polymer Materials Group, University Politehnica of Bucharest, 1-7 Gh. Polizu Street, 011061 Bucharest, RomaniaThe field of membrane materials is one of the most dynamic due to the continuously changing requirements regarding the selectivity and the upgradation of the materials developed with the constantly changing needs. Two membrane processes are essential at present, not for development, but for everyday life—desalination and hemodialysis. Hemodialysis has preserved life and increased life expectancy over the past 60–70 years for tens of millions of people with chronic kidney dysfunction. In addition to the challenges related to the efficiency and separative properties of the membranes, the biggest challenge remained and still remains the assurance of hemocompatibility—not affecting the blood during its recirculation outside the body for 4 h once every two days. This review presents the latest research carried out in the field of functionalization of polysulfone membranes (the most used polymer in the preparation of membranes for hemodialysis) with the purpose of increasing the hemocompatibility and efficiency of the separation process itself with a decreasing impact on the body.https://www.mdpi.com/2073-4360/14/6/1130hemodialysiscovalent functionalizationcomposite membranespolysulfone
spellingShingle Elena Ruxandra Radu
Stefan Ioan Voicu
Functionalized Hemodialysis Polysulfone Membranes with Improved Hemocompatibility
Polymers
hemodialysis
covalent functionalization
composite membranes
polysulfone
title Functionalized Hemodialysis Polysulfone Membranes with Improved Hemocompatibility
title_full Functionalized Hemodialysis Polysulfone Membranes with Improved Hemocompatibility
title_fullStr Functionalized Hemodialysis Polysulfone Membranes with Improved Hemocompatibility
title_full_unstemmed Functionalized Hemodialysis Polysulfone Membranes with Improved Hemocompatibility
title_short Functionalized Hemodialysis Polysulfone Membranes with Improved Hemocompatibility
title_sort functionalized hemodialysis polysulfone membranes with improved hemocompatibility
topic hemodialysis
covalent functionalization
composite membranes
polysulfone
url https://www.mdpi.com/2073-4360/14/6/1130
work_keys_str_mv AT elenaruxandraradu functionalizedhemodialysispolysulfonemembraneswithimprovedhemocompatibility
AT stefanioanvoicu functionalizedhemodialysispolysulfonemembraneswithimprovedhemocompatibility