Diagnosis and treatment of follicular lymphoma
Follicular lymphoma is a slow-growing disease exhibiting a heterogeneous clinical course, with a subset of patients experiencing a rapid disease course in the first two years and some developing disease transformation to a more aggressive phenotype. The advent of highly effective therapies ha...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SMW supporting association (Trägerverein Swiss Medical Weekly SMW)
2011-08-01
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| Series: | Swiss Medical Weekly |
| Subjects: | |
| Online Access: | https://www.smw.ch/index.php/smw/article/view/1332 |
| _version_ | 1811194086643728384 |
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| author | F Hitz A Lohri S Pederiva K Yeow S Bodis E Zucca |
| author_facet | F Hitz A Lohri S Pederiva K Yeow S Bodis E Zucca |
| author_sort | F Hitz |
| collection | DOAJ |
| description |
Follicular lymphoma is a slow-growing disease exhibiting a heterogeneous clinical course, with a subset of patients experiencing a rapid disease course in the first two years and some developing disease transformation to a more aggressive phenotype. The advent of highly effective therapies has resulted in an increasing number of patients who achieve long-term progression-free survival alongside a good quality of life. Monoclonal antibodies, such as rituximab, either alone or in combination with chemotherapy regimens or radioimmunotherapy have been used with significant improvements in outcome. New treatment strategies such as new antibodies, biologic agents or vaccination therapy are also under investigation for the treatment of relapsed or refractory disease, further expanding the available options for patients and physicians alike. This article presents an overview of the current therapeutic strategies for the management of follicular lymphoma, focusing on the issues encountered in clinical practice.
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| first_indexed | 2024-04-12T00:20:16Z |
| format | Article |
| id | doaj.art-7619f103ad864b08bc704f4f10e845ab |
| institution | Directory Open Access Journal |
| issn | 1424-3997 |
| language | English |
| last_indexed | 2024-04-12T00:20:16Z |
| publishDate | 2011-08-01 |
| publisher | SMW supporting association (Trägerverein Swiss Medical Weekly SMW) |
| record_format | Article |
| series | Swiss Medical Weekly |
| spelling | doaj.art-7619f103ad864b08bc704f4f10e845ab2022-12-22T03:55:44ZengSMW supporting association (Trägerverein Swiss Medical Weekly SMW)Swiss Medical Weekly1424-39972011-08-01141313210.4414/smw.2011.13247Diagnosis and treatment of follicular lymphomaF HitzA LohriS PederivaK YeowS BodisE Zucca Follicular lymphoma is a slow-growing disease exhibiting a heterogeneous clinical course, with a subset of patients experiencing a rapid disease course in the first two years and some developing disease transformation to a more aggressive phenotype. The advent of highly effective therapies has resulted in an increasing number of patients who achieve long-term progression-free survival alongside a good quality of life. Monoclonal antibodies, such as rituximab, either alone or in combination with chemotherapy regimens or radioimmunotherapy have been used with significant improvements in outcome. New treatment strategies such as new antibodies, biologic agents or vaccination therapy are also under investigation for the treatment of relapsed or refractory disease, further expanding the available options for patients and physicians alike. This article presents an overview of the current therapeutic strategies for the management of follicular lymphoma, focusing on the issues encountered in clinical practice. https://www.smw.ch/index.php/smw/article/view/1332consolidationfirst-line treatmentfollicular lymphomafollow-upmaintenance treatmentrelapse/refractory disease |
| spellingShingle | F Hitz A Lohri S Pederiva K Yeow S Bodis E Zucca Diagnosis and treatment of follicular lymphoma Swiss Medical Weekly consolidation first-line treatment follicular lymphoma follow-up maintenance treatment relapse/refractory disease |
| title | Diagnosis and treatment of follicular lymphoma |
| title_full | Diagnosis and treatment of follicular lymphoma |
| title_fullStr | Diagnosis and treatment of follicular lymphoma |
| title_full_unstemmed | Diagnosis and treatment of follicular lymphoma |
| title_short | Diagnosis and treatment of follicular lymphoma |
| title_sort | diagnosis and treatment of follicular lymphoma |
| topic | consolidation first-line treatment follicular lymphoma follow-up maintenance treatment relapse/refractory disease |
| url | https://www.smw.ch/index.php/smw/article/view/1332 |
| work_keys_str_mv | AT fhitz diagnosisandtreatmentoffollicularlymphoma AT alohri diagnosisandtreatmentoffollicularlymphoma AT spederiva diagnosisandtreatmentoffollicularlymphoma AT kyeow diagnosisandtreatmentoffollicularlymphoma AT sbodis diagnosisandtreatmentoffollicularlymphoma AT ezucca diagnosisandtreatmentoffollicularlymphoma |