Application of nano‐graphene oxide as nontoxic disinfectant against alpha and betacoronaviruses
Abstract New viruses are continuously emerging and recently there have been many great concerns on severe acute respiratory syndrome coronavirus (SARS‐CoV‐2). Nanographene oxide (nanoGO) has received much attention and is widely investigated to be utilised in therapy for infectious diseases by virus...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2021-11-01
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| Series: | Veterinary Medicine and Science |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/vms3.584 |
| _version_ | 1818344432604282880 |
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| author | Hee‐Chun Chung Van Giap Nguyen Cheong Ung Kim Hai‐Quynh Do Bong Kyun Park Yong Ho Park Dae‐Sub Song Aeri Kong Jae‐Chul Ryu Kyung‐Sun Kang |
| author_facet | Hee‐Chun Chung Van Giap Nguyen Cheong Ung Kim Hai‐Quynh Do Bong Kyun Park Yong Ho Park Dae‐Sub Song Aeri Kong Jae‐Chul Ryu Kyung‐Sun Kang |
| author_sort | Hee‐Chun Chung |
| collection | DOAJ |
| description | Abstract New viruses are continuously emerging and recently there have been many great concerns on severe acute respiratory syndrome coronavirus (SARS‐CoV‐2). Nanographene oxide (nanoGO) has received much attention and is widely investigated to be utilised in therapy for infectious diseases by viruses. Thus, antiviral activity of nanoGO was evaluated using the porcine epidemic diarrhoea virus (PEDV), bovine coronavirus (BCoV), and SARS‐CoV‐2, which are all Alpha‐ and Beta‐coronavirus. In a virus inhibition assay, the three viruses were inhibited by nanoGO in a dose‐dependent manner, including attempts in the presence of high serum solution which partially mimicked biological fluid. |
| first_indexed | 2024-12-13T16:46:23Z |
| format | Article |
| id | doaj.art-761a75a859b74356b5f72795145009c3 |
| institution | Directory Open Access Journal |
| issn | 2053-1095 |
| language | English |
| last_indexed | 2024-12-13T16:46:23Z |
| publishDate | 2021-11-01 |
| publisher | Wiley |
| record_format | Article |
| series | Veterinary Medicine and Science |
| spelling | doaj.art-761a75a859b74356b5f72795145009c32022-12-21T23:38:08ZengWileyVeterinary Medicine and Science2053-10952021-11-01762434243910.1002/vms3.584Application of nano‐graphene oxide as nontoxic disinfectant against alpha and betacoronavirusesHee‐Chun Chung0Van Giap Nguyen1Cheong Ung Kim2Hai‐Quynh Do3Bong Kyun Park4Yong Ho Park5Dae‐Sub Song6Aeri Kong7Jae‐Chul Ryu8Kyung‐Sun Kang9Department of Veterinary Medicine Virology Lab College of Veterinary Medicine and Research Institute for Veterinary Science Seoul National University GwanAk‐Gu Seoul KoreaFaculty of Veterinary Medicine Department of Veterinary Microbiology and Infectious Diseases Vietnam National University of Agriculture Hanoi VietnamDepartment of Veterinary Microbiology College of Veterinary Medicine and Research Institute for Veterinary Science Seoul National University Seoul Republic of KoreaDepartment of Veterinary Medicine Virology Lab College of Veterinary Medicine and Research Institute for Veterinary Science Seoul National University GwanAk‐Gu Seoul KoreaDepartment of Veterinary Medicine Virology Lab College of Veterinary Medicine and Research Institute for Veterinary Science Seoul National University GwanAk‐Gu Seoul KoreaDepartment of Veterinary Microbiology College of Veterinary Medicine and Research Institute for Veterinary Science Seoul National University Seoul Republic of KoreaDepartment of Pharmacy College of Pharmacy Korea University Sejong Republic of KoreaDepartment of Medical Science University of California Los Angeles California USAAdult Stem Cell Research Center and Research Institute for Veterinary Science College of Veterinary Medicine Seoul National University Seoul Republic of KoreaAdult Stem Cell Research Center and Research Institute for Veterinary Science College of Veterinary Medicine Seoul National University Seoul Republic of KoreaAbstract New viruses are continuously emerging and recently there have been many great concerns on severe acute respiratory syndrome coronavirus (SARS‐CoV‐2). Nanographene oxide (nanoGO) has received much attention and is widely investigated to be utilised in therapy for infectious diseases by viruses. Thus, antiviral activity of nanoGO was evaluated using the porcine epidemic diarrhoea virus (PEDV), bovine coronavirus (BCoV), and SARS‐CoV‐2, which are all Alpha‐ and Beta‐coronavirus. In a virus inhibition assay, the three viruses were inhibited by nanoGO in a dose‐dependent manner, including attempts in the presence of high serum solution which partially mimicked biological fluid.https://doi.org/10.1002/vms3.584antiviral activitycoronavirusesnano‐graphene oxide |
| spellingShingle | Hee‐Chun Chung Van Giap Nguyen Cheong Ung Kim Hai‐Quynh Do Bong Kyun Park Yong Ho Park Dae‐Sub Song Aeri Kong Jae‐Chul Ryu Kyung‐Sun Kang Application of nano‐graphene oxide as nontoxic disinfectant against alpha and betacoronaviruses Veterinary Medicine and Science antiviral activity coronaviruses nano‐graphene oxide |
| title | Application of nano‐graphene oxide as nontoxic disinfectant against alpha and betacoronaviruses |
| title_full | Application of nano‐graphene oxide as nontoxic disinfectant against alpha and betacoronaviruses |
| title_fullStr | Application of nano‐graphene oxide as nontoxic disinfectant against alpha and betacoronaviruses |
| title_full_unstemmed | Application of nano‐graphene oxide as nontoxic disinfectant against alpha and betacoronaviruses |
| title_short | Application of nano‐graphene oxide as nontoxic disinfectant against alpha and betacoronaviruses |
| title_sort | application of nano graphene oxide as nontoxic disinfectant against alpha and betacoronaviruses |
| topic | antiviral activity coronaviruses nano‐graphene oxide |
| url | https://doi.org/10.1002/vms3.584 |
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