Role of TLR4 signaling on Porphyromonas gingivalis LPS-induced cardiac dysfunction in mice.

Role of TLR4 signaling on Porphyromonas gingivalis LPS-induced cardiac dysfunction in mice.

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Oral infections, particularly periodontitis, are a well-established risk factor for cardiovascular diseases, although the molecular mechanisms involved remain elusive. The aims of the present study were to investigate the effects of lipopolysaccharide derived from Porphyromonas gingivalis (PG-LPS) o...

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Bibliographic Details
Main Authors: Ichiro Matsuo, Naoya Kawamura, Yoshiki Ohnuki, Kenji Suita, Misao Ishikawa, Takehiro Matsubara, Yasumasa Mototani, Aiko Ito, Yoshio Hayakawa, Megumi Nariyama, Akinaka Morii, Kenichi Kiyomoto, Michinori Tsunoda, Kazuhiro Gomi, Satoshi Okumura
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0258823

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