Safety of sildenafil in premature infants at risk of bronchopulmonary dysplasia: Rationale and methods of a phase II randomized trial

Safety of sildenafil in premature infants at risk of bronchopulmonary dysplasia: Rationale and methods of a phase II randomized trial

Bronchopulmonary dysplasia (BPD) is a disease of chronic respiratory insufficiency stemming from premature birth and iatrogenic lung injury leading to alveolar simplification, impaired alveolar-capillary development, interstitial fibrosis, and often pulmonary hypertension. BPD is the most common pul...

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Bibliographic Details
Main Authors: Jason E. Lang, Chi D. Hornik, Karen Martz, Juliana Jacangelo, Ravinder Anand, Rachel Greenberg, Christoph Hornik, Kanecia Zimmerman, P. Brian Smith, Daniel K. Benjamin, Matthew Laughon
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Contemporary Clinical Trials Communications
Subjects:
Sildenafil
Bronchopulmonary dysplasia
Prematurity
Online Access:http://www.sciencedirect.com/science/article/pii/S2451865422001429

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