Only 32.3% of Breast Cancer Families with Pathogenic Variants in Cancer Genes Utilized Cascade Genetic Testing

Only 32.3% of Breast Cancer Families with Pathogenic Variants in Cancer Genes Utilized Cascade Genetic Testing

Background: Hereditary cancer predisposition syndromes are responsible for approximately 5–10% of all diagnosed cancer cases. In order to identify individuals at risk in a cost-efficient manner, family members of individuals carrying pathogenic alterations are tested only for the specific variant th...

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Bibliographic Details
Main Authors: Konstantinos Agiannitopoulos, Kevisa Potska, Anastasia Katseli, Christina Ntogka, Georgios N. Tsaousis, Georgia Pepe, Dimitra Bouzarelou, Nikolaos Tsoulos, Athanasios Papathanasiou, Dimitrios Ziogas, Vassileios Venizelos, Christos Markopoulos, Rodoniki Iosifidou, Sofia Karageorgopoulou, Stylianos Giassas, Ioannis Natsiopoulos, Konstantinos Papazisis, Maria Vasilaki-Antonatou, Amanta Psyrri, Anna Koumarianou, Dimitrios Matthaios, Eleni Zairi, Alexandru Blidaru, Eugeniu Banu, Dan Corneliu Jinga, Şahin Laçin, Mustafa Özdoğan, Eirini Papadopoulou, George Nasioulas
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Cancers
Subjects:
cascade family testing
hereditary breast cancer
next-generation sequencing
Online Access:https://www.mdpi.com/2072-6694/15/21/5218

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