A case report of Xanthogranulomatous Cholecystitis

Xanthogranulomatous cholecystitis is a benign, uncommon type of chronic cholecystitis manifested by focal or diffuse severe inflammatory process of the gallbladder (GB).  It is inflammatory disease of the gallbladder characterized by the infiltrations of plasma cells, lipid-laden histiocytes, and th...

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Main Authors: Ahmed Hassan Abdelmoneim, Adham Darweesh, Avin Kounsal, Abdelwahed Samir Abougazia
Format: Article
Language:English
Published: Albanian Society for Trauma and Emergency Surgery 2021-01-01
Series:Albanian Journal of Trauma and Emergency Surgery
Subjects:
Online Access:https://journal.astes.org.al/index.php/AJTES/article/view/166
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author Ahmed Hassan Abdelmoneim
Adham Darweesh
Avin Kounsal
Abdelwahed Samir Abougazia
author_facet Ahmed Hassan Abdelmoneim
Adham Darweesh
Avin Kounsal
Abdelwahed Samir Abougazia
author_sort Ahmed Hassan Abdelmoneim
collection DOAJ
description Xanthogranulomatous cholecystitis is a benign, uncommon type of chronic cholecystitis manifested by focal or diffuse severe inflammatory process of the gallbladder (GB).  It is inflammatory disease of the gallbladder characterized by the infiltrations of plasma cells, lipid-laden histiocytes, and the fibroblasts proliferation in GB wall. Gallstones are present in all patients, and like most symptomatic gallbladder diseases, there is a female predominance. It is an active inflammatory process which could leads to significant morbidity. The term Xanthogranulomatous cholecystitis was initially proposed by Goodman and Ishak in 1981. The pathogenesis of XGC is the rupture of Rokitansky-Aschoff sinuses and extravasation of bile into the muscular layer. The rupture of the serosa results in adhesion to the adjacent liver, duodenum, and transverse colon.  Macroscopically, it appears like yellowish masses in the wall of the GB. Radiologically it is an important mimic of gallbladder carcinoma.
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spelling doaj.art-76267bc50221416ba316748a4bb8fe322022-12-21T20:41:08ZengAlbanian Society for Trauma and Emergency SurgeryAlbanian Journal of Trauma and Emergency Surgery2521-87782616-49222021-01-015110.32391/ajtes.v5i1.166A case report of Xanthogranulomatous CholecystitisAhmed Hassan Abdelmoneim0Adham DarweeshAvin KounsalAbdelwahed Samir AbougaziamXanthogranulomatous cholecystitis is a benign, uncommon type of chronic cholecystitis manifested by focal or diffuse severe inflammatory process of the gallbladder (GB).  It is inflammatory disease of the gallbladder characterized by the infiltrations of plasma cells, lipid-laden histiocytes, and the fibroblasts proliferation in GB wall. Gallstones are present in all patients, and like most symptomatic gallbladder diseases, there is a female predominance. It is an active inflammatory process which could leads to significant morbidity. The term Xanthogranulomatous cholecystitis was initially proposed by Goodman and Ishak in 1981. The pathogenesis of XGC is the rupture of Rokitansky-Aschoff sinuses and extravasation of bile into the muscular layer. The rupture of the serosa results in adhesion to the adjacent liver, duodenum, and transverse colon.  Macroscopically, it appears like yellowish masses in the wall of the GB. Radiologically it is an important mimic of gallbladder carcinoma.https://journal.astes.org.al/index.php/AJTES/article/view/166Xanthogranulomatous cholecystitis, gallbladder MRI, GB carcinoma, Chronic cholecystitis.
spellingShingle Ahmed Hassan Abdelmoneim
Adham Darweesh
Avin Kounsal
Abdelwahed Samir Abougazia
A case report of Xanthogranulomatous Cholecystitis
Albanian Journal of Trauma and Emergency Surgery
Xanthogranulomatous cholecystitis, gallbladder MRI, GB carcinoma, Chronic cholecystitis.
title A case report of Xanthogranulomatous Cholecystitis
title_full A case report of Xanthogranulomatous Cholecystitis
title_fullStr A case report of Xanthogranulomatous Cholecystitis
title_full_unstemmed A case report of Xanthogranulomatous Cholecystitis
title_short A case report of Xanthogranulomatous Cholecystitis
title_sort case report of xanthogranulomatous cholecystitis
topic Xanthogranulomatous cholecystitis, gallbladder MRI, GB carcinoma, Chronic cholecystitis.
url https://journal.astes.org.al/index.php/AJTES/article/view/166
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