Visceral leishmaniasis in 26 HIV-negative adults
<p>Abstract</p> <p>Background</p> <p>Visceral leishmaniasis is a notifiable parasitic disease that had increased in incidence in our region on the past few years. It is common in children. In adults, it occurs more on a background of immunodeficiency, and frequently wit...
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| Format: | Article |
| Language: | English |
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BMC
2011-10-01
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| Series: | BMC Research Notes |
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| Online Access: | http://www.biomedcentral.com/1756-0500/4/389 |
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| author | Berrady Rhizlane Amrani Moncef Alami Meryem Filali Ahmed B Lahlou Hazar Rabhi Samira Bono Wafaa |
| author_facet | Berrady Rhizlane Amrani Moncef Alami Meryem Filali Ahmed B Lahlou Hazar Rabhi Samira Bono Wafaa |
| author_sort | Berrady Rhizlane |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>Visceral leishmaniasis is a notifiable parasitic disease that had increased in incidence in our region on the past few years. It is common in children. In adults, it occurs more on a background of immunodeficiency, and frequently with incomplete clinical manifestations, making the diagnosis complicated.</p> <p>Findings</p> <p>The aim of our study is to reveal different features of visceral leishmaniasis in adults, through the analysis of its epidemiological, clinical and biological parameters, in a group of 26 patients. No one was infected with HIV or under immunosuppressive therapy Clinical presentation was generally conservative, but there was few differences in adults compared to children, concerning both the clinical symptoms and the laboratory parameters. Diagnosis was provided by direct examination of bone marrow smears in 24 cases (sensitivity 92%), and anti-leishmanial serology in the others.</p> <p>Conclusion</p> <p>We should think to the diagnosis of VL even if the patient is not known immunocompromised, and even if the clinical is incomplete, to avoid a delay of care which can lead to serious complications.</p> |
| first_indexed | 2024-12-10T15:32:15Z |
| format | Article |
| id | doaj.art-762add03d0564a35835e8694df6b0437 |
| institution | Directory Open Access Journal |
| issn | 1756-0500 |
| language | English |
| last_indexed | 2024-12-10T15:32:15Z |
| publishDate | 2011-10-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Research Notes |
| spelling | doaj.art-762add03d0564a35835e8694df6b04372022-12-22T01:43:21ZengBMCBMC Research Notes1756-05002011-10-014138910.1186/1756-0500-4-389Visceral leishmaniasis in 26 HIV-negative adultsBerrady RhizlaneAmrani MoncefAlami MeryemFilali Ahmed BLahlou HazarRabhi SamiraBono Wafaa<p>Abstract</p> <p>Background</p> <p>Visceral leishmaniasis is a notifiable parasitic disease that had increased in incidence in our region on the past few years. It is common in children. In adults, it occurs more on a background of immunodeficiency, and frequently with incomplete clinical manifestations, making the diagnosis complicated.</p> <p>Findings</p> <p>The aim of our study is to reveal different features of visceral leishmaniasis in adults, through the analysis of its epidemiological, clinical and biological parameters, in a group of 26 patients. No one was infected with HIV or under immunosuppressive therapy Clinical presentation was generally conservative, but there was few differences in adults compared to children, concerning both the clinical symptoms and the laboratory parameters. Diagnosis was provided by direct examination of bone marrow smears in 24 cases (sensitivity 92%), and anti-leishmanial serology in the others.</p> <p>Conclusion</p> <p>We should think to the diagnosis of VL even if the patient is not known immunocompromised, and even if the clinical is incomplete, to avoid a delay of care which can lead to serious complications.</p>http://www.biomedcentral.com/1756-0500/4/389visceral leishmaniasisHIV-negative adultsbone marrow aspirateimmunofluorescent antibody test |
| spellingShingle | Berrady Rhizlane Amrani Moncef Alami Meryem Filali Ahmed B Lahlou Hazar Rabhi Samira Bono Wafaa Visceral leishmaniasis in 26 HIV-negative adults BMC Research Notes visceral leishmaniasis HIV-negative adults bone marrow aspirate immunofluorescent antibody test |
| title | Visceral leishmaniasis in 26 HIV-negative adults |
| title_full | Visceral leishmaniasis in 26 HIV-negative adults |
| title_fullStr | Visceral leishmaniasis in 26 HIV-negative adults |
| title_full_unstemmed | Visceral leishmaniasis in 26 HIV-negative adults |
| title_short | Visceral leishmaniasis in 26 HIV-negative adults |
| title_sort | visceral leishmaniasis in 26 hiv negative adults |
| topic | visceral leishmaniasis HIV-negative adults bone marrow aspirate immunofluorescent antibody test |
| url | http://www.biomedcentral.com/1756-0500/4/389 |
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