Identifying quantitative trait loci affecting resistance to congenital hypothyroidism in 129/SvJcl strain mice.

Identifying quantitative trait loci affecting resistance to congenital hypothyroidism in 129/SvJcl strain mice.

Tyrosylprotein sulfotransferase 2 (TPST2) is one of the enzymes responsible for tyrosine O-sulfation and catalyzes the sulfation of the specific tyrosine residue of thyroid stimulating hormone receptor (TSHR). Since this modification is indispensable for the activation of TSH signaling, a non-functi...

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Bibliographic Details
Main Authors: Yayoi Hosoda, Nobuya Sasaki, Yayoi Kameda, Daisuke Torigoe, Takashi Agui
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3267771?pdf=render

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