GRB2 is a BECN1 interacting protein that regulates autophagy
Abstract GRB2 is an adaptor protein of HER2 (and several other tyrosine kinases), which we identified as a novel BECN1 (Beclin 1) interacting partner. GRB2 co-immunoprecipitated with BECN1 in several breast cancer cell lines and regulates autophagy through a mechanism involving the modulation of the...
| Үндсэн зохиолчид: | , , , , , , , , , , , , |
|---|---|
| Формат: | Өгүүллэг |
| Хэл сонгох: | English |
| Хэвлэсэн: |
Nature Publishing Group
2024-01-01
|
| Цуврал: | Cell Death and Disease |
| Онлайн хандалт: | https://doi.org/10.1038/s41419-023-06387-7 |