Bacteriophages of the Order <i>Crassvirales</i>: What Do We Currently Know about This Keystone Component of the Human Gut Virome?

The order <i>Crassvirales</i> comprises dsDNA bacteriophages infecting bacteria in the phylum Bacteroidetes that are found in a variety of environments but are especially prevalent in the mammalian gut. This review summarises available information on the genomics, diversity, taxonomy, an...

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Bibliographic Details
Main Authors: Linda Smith, Ekaterina Goldobina, Bianca Govi, Andrey N. Shkoporov
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/13/4/584
Description
Summary:The order <i>Crassvirales</i> comprises dsDNA bacteriophages infecting bacteria in the phylum Bacteroidetes that are found in a variety of environments but are especially prevalent in the mammalian gut. This review summarises available information on the genomics, diversity, taxonomy, and ecology of this largely uncultured viral taxon. With experimental data available from a handful of cultured representatives, the review highlights key properties of virion morphology, infection, gene expression and replication processes, and phage-host dynamics.
ISSN:2218-273X