Comparative Clinical Study of Suprathel<sup>®</sup> and Jelonet<sup>®</sup> Wound Dressings in Burn Wound Healing after Enzymatic Debridement
Following the enzymatic debridement of deep dermal burns, the choice of wound dressing is crucial for providing an adequate environment and suitable conditions for rapid wound healing. As Suprathel<sup>®</sup> and fatty gauze (Jelonet<sup>®</sup>) are the most commonly used d...
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| Format: | Article |
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MDPI AG
2023-09-01
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| Series: | Biomedicines |
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| Online Access: | https://www.mdpi.com/2227-9059/11/10/2593 |
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| author | Wolfram Heitzmann Mitja Mossing Paul Christian Fuchs Jan Akkan Harun Seyhan Gerrit Grieb Christian Opländer Jennifer Lynn Schiefer |
| author_facet | Wolfram Heitzmann Mitja Mossing Paul Christian Fuchs Jan Akkan Harun Seyhan Gerrit Grieb Christian Opländer Jennifer Lynn Schiefer |
| author_sort | Wolfram Heitzmann |
| collection | DOAJ |
| description | Following the enzymatic debridement of deep dermal burns, the choice of wound dressing is crucial for providing an adequate environment and suitable conditions for rapid wound healing. As Suprathel<sup>®</sup> and fatty gauze (Jelonet<sup>®</sup>) are the most commonly used dressings in burn centers, the aim of this study is to compare Suprathel<sup>®</sup> and Jelonet<sup>®</sup> in the treatment of deep dermal burns after enzymatic debridement with respect to wound healing, patient comfort, and pain. A total of 23 patients with deep dermal burns of the hand or foot (mean total body surface area of 4.31%) were included in this prospective, unicentric, open, comparative, and intra-individual clinical study. After enzymatic debridement, wounds were divided into two areas: one was treated with Suprathel<sup>®</sup> and the other with Jelonet<sup>®</sup>. Suprathel<sup>®</sup> remained on the wounds without dressing changes while Jelonet<sup>®</sup> was regularly changed. Wound healing, infection, bleeding, exudation, time for dressing changes, and pain were documented (from days 2 to 48) after injury. Satisfactory results were obtained in 22 cases; only one patient had to undergo a second debridement followed by skin grafting. No significant difference in time to final wound healing could be observed (18–19 d). Patients reported significantly less pain during the dressing changes for Suprathel<sup>®</sup> compared to Jelonet<sup>®</sup>. Furthermore, the wound areas treated with Suprathel<sup>®</sup> showed significantly less exudation and bleeding. Wound infections rarely occurred in both groups. In conclusion, the authors found that both wound dressings could be used to achieve safe and rapid wound healing after the enzymatic debridement of deep dermal burns of the hands and feet. However, compared to Jelonet<sup>®</sup>, Suprathel<sup>®</sup> showed superior results in terms of patient comfort and pain reduction. |
| first_indexed | 2024-03-10T21:25:31Z |
| format | Article |
| id | doaj.art-76353d7406e0454293b2e701067b5d36 |
| institution | Directory Open Access Journal |
| issn | 2227-9059 |
| language | English |
| last_indexed | 2024-03-10T21:25:31Z |
| publishDate | 2023-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomedicines |
| spelling | doaj.art-76353d7406e0454293b2e701067b5d362023-11-19T15:44:14ZengMDPI AGBiomedicines2227-90592023-09-011110259310.3390/biomedicines11102593Comparative Clinical Study of Suprathel<sup>®</sup> and Jelonet<sup>®</sup> Wound Dressings in Burn Wound Healing after Enzymatic DebridementWolfram Heitzmann0Mitja Mossing1Paul Christian Fuchs2Jan Akkan3Harun Seyhan4Gerrit Grieb5Christian Opländer6Jennifer Lynn Schiefer7Clinic of Plastic, Reconstructive, Hand and Burn Surgery, Cologne-Merheim Hospital, Witten/Herdecke University, 51109 Cologne, GermanyClinic of Plastic, Reconstructive, Hand and Burn Surgery, Cologne-Merheim Hospital, Witten/Herdecke University, 51109 Cologne, GermanyClinic of Plastic, Reconstructive, Hand and Burn Surgery, Cologne-Merheim Hospital, Witten/Herdecke University, 51109 Cologne, GermanyClinic of Plastic, Reconstructive, Hand and Burn Surgery, Cologne-Merheim Hospital, Witten/Herdecke University, 51109 Cologne, GermanyClinic of Plastic, Reconstructive, Hand and Burn Surgery, Cologne-Merheim Hospital, Witten/Herdecke University, 51109 Cologne, GermanyDepartment of Plastic Surgery and Hand Surgery, Gemeinschaftskrankenhaus Havelhoehe, Teaching Hospital of the Charité Berlin, Kladower Damm 221, 14089 Berlin, GermanyInstitute for Research in Operative Medicine (IFOM), Cologne-Merheim Hospital, Witten/Herdecke University, Ostmerheimer Str. 200, 51109 Cologne, GermanyClinic of Plastic, Reconstructive, Hand and Burn Surgery, Cologne-Merheim Hospital, Witten/Herdecke University, 51109 Cologne, GermanyFollowing the enzymatic debridement of deep dermal burns, the choice of wound dressing is crucial for providing an adequate environment and suitable conditions for rapid wound healing. As Suprathel<sup>®</sup> and fatty gauze (Jelonet<sup>®</sup>) are the most commonly used dressings in burn centers, the aim of this study is to compare Suprathel<sup>®</sup> and Jelonet<sup>®</sup> in the treatment of deep dermal burns after enzymatic debridement with respect to wound healing, patient comfort, and pain. A total of 23 patients with deep dermal burns of the hand or foot (mean total body surface area of 4.31%) were included in this prospective, unicentric, open, comparative, and intra-individual clinical study. After enzymatic debridement, wounds were divided into two areas: one was treated with Suprathel<sup>®</sup> and the other with Jelonet<sup>®</sup>. Suprathel<sup>®</sup> remained on the wounds without dressing changes while Jelonet<sup>®</sup> was regularly changed. Wound healing, infection, bleeding, exudation, time for dressing changes, and pain were documented (from days 2 to 48) after injury. Satisfactory results were obtained in 22 cases; only one patient had to undergo a second debridement followed by skin grafting. No significant difference in time to final wound healing could be observed (18–19 d). Patients reported significantly less pain during the dressing changes for Suprathel<sup>®</sup> compared to Jelonet<sup>®</sup>. Furthermore, the wound areas treated with Suprathel<sup>®</sup> showed significantly less exudation and bleeding. Wound infections rarely occurred in both groups. In conclusion, the authors found that both wound dressings could be used to achieve safe and rapid wound healing after the enzymatic debridement of deep dermal burns of the hands and feet. However, compared to Jelonet<sup>®</sup>, Suprathel<sup>®</sup> showed superior results in terms of patient comfort and pain reduction.https://www.mdpi.com/2227-9059/11/10/2593Jelonet<sup>®</sup>Suprathel<sup>®</sup>deep dermal burnsenzymatic debridementwound healing |
| spellingShingle | Wolfram Heitzmann Mitja Mossing Paul Christian Fuchs Jan Akkan Harun Seyhan Gerrit Grieb Christian Opländer Jennifer Lynn Schiefer Comparative Clinical Study of Suprathel<sup>®</sup> and Jelonet<sup>®</sup> Wound Dressings in Burn Wound Healing after Enzymatic Debridement Biomedicines Jelonet<sup>®</sup> Suprathel<sup>®</sup> deep dermal burns enzymatic debridement wound healing |
| title | Comparative Clinical Study of Suprathel<sup>®</sup> and Jelonet<sup>®</sup> Wound Dressings in Burn Wound Healing after Enzymatic Debridement |
| title_full | Comparative Clinical Study of Suprathel<sup>®</sup> and Jelonet<sup>®</sup> Wound Dressings in Burn Wound Healing after Enzymatic Debridement |
| title_fullStr | Comparative Clinical Study of Suprathel<sup>®</sup> and Jelonet<sup>®</sup> Wound Dressings in Burn Wound Healing after Enzymatic Debridement |
| title_full_unstemmed | Comparative Clinical Study of Suprathel<sup>®</sup> and Jelonet<sup>®</sup> Wound Dressings in Burn Wound Healing after Enzymatic Debridement |
| title_short | Comparative Clinical Study of Suprathel<sup>®</sup> and Jelonet<sup>®</sup> Wound Dressings in Burn Wound Healing after Enzymatic Debridement |
| title_sort | comparative clinical study of suprathel sup r sup and jelonet sup r sup wound dressings in burn wound healing after enzymatic debridement |
| topic | Jelonet<sup>®</sup> Suprathel<sup>®</sup> deep dermal burns enzymatic debridement wound healing |
| url | https://www.mdpi.com/2227-9059/11/10/2593 |
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