A child with anorexia nervosa presenting with severe infection with cytopenia and hemophagocytosis: a case report

Abstract Background Patients with anorexia nervosa in the acute phase have physical complications, such as infectious disease. Although hemophagocytic syndrome due to infection is a rare complication in anorexia nervosa, early identification for hemophagocytosis is important for avoiding a life-thre...

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Main Authors: Masao Suda, Shinichiro Nagamitsu, Masahiro Kinosita, Michiko Matsuoka, Shuichi Ozono, Yasushi Otsu, Yushiro Yamashita, Toyojiro Matsuishi
Format: Article
Language:English
Published: BMC 2017-09-01
Series:BioPsychoSocial Medicine
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13030-017-0108-6
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author Masao Suda
Shinichiro Nagamitsu
Masahiro Kinosita
Michiko Matsuoka
Shuichi Ozono
Yasushi Otsu
Yushiro Yamashita
Toyojiro Matsuishi
author_facet Masao Suda
Shinichiro Nagamitsu
Masahiro Kinosita
Michiko Matsuoka
Shuichi Ozono
Yasushi Otsu
Yushiro Yamashita
Toyojiro Matsuishi
author_sort Masao Suda
collection DOAJ
description Abstract Background Patients with anorexia nervosa in the acute phase have physical complications, such as infectious disease. Although hemophagocytic syndrome due to infection is a rare complication in anorexia nervosa, early identification for hemophagocytosis is important for avoiding a life-threatening condition. Case presentation We report a case of a 12-year-old girl with anorexia nervosa presenting with infection with cytopenia and hemophagocytosis during initial nutritional therapy. She developed pyrexia, abdominal pain, and diarrhea during inpatient treatment. Although intravenous antibiotics were administered, the symptoms persisted. Acinetobacter baumannii was detected in blood culture. Hemophagocytosis was present in the bone marrow. Gamma globulin therapy was effective, with improvement in symptoms and cytopenia. Conclusions Although our case did not fulfill the criteria of hemophagocytic syndrome, clinicians should consider severe infection in anorexia nervosa with cytopenia and hemophagocytosis.
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spelling doaj.art-7635e864d49b4ecb875b2cf530c47c672022-12-22T01:14:01ZengBMCBioPsychoSocial Medicine1751-07592017-09-011111410.1186/s13030-017-0108-6A child with anorexia nervosa presenting with severe infection with cytopenia and hemophagocytosis: a case reportMasao Suda0Shinichiro Nagamitsu1Masahiro Kinosita2Michiko Matsuoka3Shuichi Ozono4Yasushi Otsu5Yushiro Yamashita6Toyojiro Matsuishi7Department of Pediatrics and Child Health, Kurume University School of MedicineDepartment of Pediatrics and Child Health, Kurume University School of MedicineDepartment of Pediatrics and Child Health, Kurume University School of MedicineDepartment of Psychiatry, Kurume University School of MedicineDepartment of Pediatrics and Child Health, Kurume University School of MedicineDepartment of Pediatrics and Child Health, Kurume University School of MedicineDepartment of Pediatrics and Child Health, Kurume University School of MedicineDepartment of Pediatrics and Child Health, Kurume University School of MedicineAbstract Background Patients with anorexia nervosa in the acute phase have physical complications, such as infectious disease. Although hemophagocytic syndrome due to infection is a rare complication in anorexia nervosa, early identification for hemophagocytosis is important for avoiding a life-threatening condition. Case presentation We report a case of a 12-year-old girl with anorexia nervosa presenting with infection with cytopenia and hemophagocytosis during initial nutritional therapy. She developed pyrexia, abdominal pain, and diarrhea during inpatient treatment. Although intravenous antibiotics were administered, the symptoms persisted. Acinetobacter baumannii was detected in blood culture. Hemophagocytosis was present in the bone marrow. Gamma globulin therapy was effective, with improvement in symptoms and cytopenia. Conclusions Although our case did not fulfill the criteria of hemophagocytic syndrome, clinicians should consider severe infection in anorexia nervosa with cytopenia and hemophagocytosis.http://link.springer.com/article/10.1186/s13030-017-0108-6Anorexia nervosaSevere infectionHemophagocytosisAcinetobacter baumannii
spellingShingle Masao Suda
Shinichiro Nagamitsu
Masahiro Kinosita
Michiko Matsuoka
Shuichi Ozono
Yasushi Otsu
Yushiro Yamashita
Toyojiro Matsuishi
A child with anorexia nervosa presenting with severe infection with cytopenia and hemophagocytosis: a case report
BioPsychoSocial Medicine
Anorexia nervosa
Severe infection
Hemophagocytosis
Acinetobacter baumannii
title A child with anorexia nervosa presenting with severe infection with cytopenia and hemophagocytosis: a case report
title_full A child with anorexia nervosa presenting with severe infection with cytopenia and hemophagocytosis: a case report
title_fullStr A child with anorexia nervosa presenting with severe infection with cytopenia and hemophagocytosis: a case report
title_full_unstemmed A child with anorexia nervosa presenting with severe infection with cytopenia and hemophagocytosis: a case report
title_short A child with anorexia nervosa presenting with severe infection with cytopenia and hemophagocytosis: a case report
title_sort child with anorexia nervosa presenting with severe infection with cytopenia and hemophagocytosis a case report
topic Anorexia nervosa
Severe infection
Hemophagocytosis
Acinetobacter baumannii
url http://link.springer.com/article/10.1186/s13030-017-0108-6
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