Alert Germ Infections: Chest X-ray and CT Findings in Hospitalized Patients Affected by Multidrug-Resistant <i>Acinetobacter baumannii</i> Pneumonia
Acinetobacter baumannii (Ab) is an opportunistic Gram-negative pathogen intrinsically resistant to many antimicrobials. The aim of this retrospective study was to describe the imaging features on chest X-ray (CXR) and computed tomography (CT) scans in hospitalized patients with multidrug-resistant (...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-06-01
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| Series: | Tomography |
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| Online Access: | https://www.mdpi.com/2379-139X/8/3/126 |
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| author | Raffaella Capasso Antonio Pinto Nicola Serra Umberto Atripaldi Adele Corcione Giorgio Bocchini Salvatore Guarino Roberta Lieto Gaetano Rea Giacomo Sica Tullio Valente |
| author_facet | Raffaella Capasso Antonio Pinto Nicola Serra Umberto Atripaldi Adele Corcione Giorgio Bocchini Salvatore Guarino Roberta Lieto Gaetano Rea Giacomo Sica Tullio Valente |
| author_sort | Raffaella Capasso |
| collection | DOAJ |
| description | Acinetobacter baumannii (Ab) is an opportunistic Gram-negative pathogen intrinsically resistant to many antimicrobials. The aim of this retrospective study was to describe the imaging features on chest X-ray (CXR) and computed tomography (CT) scans in hospitalized patients with multidrug-resistant (MDR) Ab pneumonia. CXR and CT findings were graded on a three-point scale: 1 represents normal attenuation, 2 represents ground-glass attenuation, and 3 represents consolidation. For each lung zone, with a total of six lung zones in each patient, the extent of disease was graded using a five-point scale: 0, no involvement; 1, involving 25% of the zone; 2, 25–50%; 3, 50–75%; and 4, involving >75% of the zone. Points from all zones were added for a final total cumulative score ranging from 0 to 72. Among 94 patients who tested positive for MDR Ab and underwent CXR (males 52.9%, females 47.1%; mean age 64.2 years; range 1–90 years), 68 patients underwent both CXR and chest CT examinations. The percentage of patients with a positive CT score was significantly higher than that obtained on CXR (67.65% > 35.94%, <i>p</i>-value = 0.00258). CT score (21.88 ± 15.77) was significantly (<i>p</i>-value = 0.0014) higher than CXR score (15.06 ± 18.29). CXR and CT revealed prevalent bilateral abnormal findings mainly located in the inferior and middle zones of the lungs. They primarily consisted of peripheral ground-glass opacities and consolidations which predominated on CXR and CT, respectively. |
| first_indexed | 2024-03-10T01:04:32Z |
| format | Article |
| id | doaj.art-76393de436734bc3b8018b871eb5d87a |
| institution | Directory Open Access Journal |
| issn | 2379-1381 2379-139X |
| language | English |
| last_indexed | 2024-03-10T01:04:32Z |
| publishDate | 2022-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Tomography |
| spelling | doaj.art-76393de436734bc3b8018b871eb5d87a2023-11-23T14:28:35ZengMDPI AGTomography2379-13812379-139X2022-06-01831534154310.3390/tomography8030126Alert Germ Infections: Chest X-ray and CT Findings in Hospitalized Patients Affected by Multidrug-Resistant <i>Acinetobacter baumannii</i> PneumoniaRaffaella Capasso0Antonio Pinto1Nicola Serra2Umberto Atripaldi3Adele Corcione4Giorgio Bocchini5Salvatore Guarino6Roberta Lieto7Gaetano Rea8Giacomo Sica9Tullio Valente10Department of Radiology, CTO Hospital, Azienda Ospedaliera dei Colli, 80131 Naples, ItalyDepartment of Radiology, CTO Hospital, Azienda Ospedaliera dei Colli, 80131 Naples, ItalyDepartment of Public Health, University Federico II of Naples, 80138 Napoli, ItalyDepartment of Radiology, Monaldi Hospital, Azienda Ospedaliera dei Colli, 80131 Naples, ItalyDepartment of Translational Medical Sciences, Section of Pediatrics, University Federico II of Naples, 80138 Napoli, ItalyDepartment of Radiology, Monaldi Hospital, Azienda Ospedaliera dei Colli, 80131 Naples, ItalyDepartment of Radiology, Monaldi Hospital, Azienda Ospedaliera dei Colli, 80131 Naples, ItalyDepartment of Radiology, Monaldi Hospital, Azienda Ospedaliera dei Colli, 80131 Naples, ItalyDepartment of Radiology, Monaldi Hospital, Azienda Ospedaliera dei Colli, 80131 Naples, ItalyDepartment of Radiology, Monaldi Hospital, Azienda Ospedaliera dei Colli, 80131 Naples, ItalyDepartment of Radiology, Monaldi Hospital, Azienda Ospedaliera dei Colli, 80131 Naples, ItalyAcinetobacter baumannii (Ab) is an opportunistic Gram-negative pathogen intrinsically resistant to many antimicrobials. The aim of this retrospective study was to describe the imaging features on chest X-ray (CXR) and computed tomography (CT) scans in hospitalized patients with multidrug-resistant (MDR) Ab pneumonia. CXR and CT findings were graded on a three-point scale: 1 represents normal attenuation, 2 represents ground-glass attenuation, and 3 represents consolidation. For each lung zone, with a total of six lung zones in each patient, the extent of disease was graded using a five-point scale: 0, no involvement; 1, involving 25% of the zone; 2, 25–50%; 3, 50–75%; and 4, involving >75% of the zone. Points from all zones were added for a final total cumulative score ranging from 0 to 72. Among 94 patients who tested positive for MDR Ab and underwent CXR (males 52.9%, females 47.1%; mean age 64.2 years; range 1–90 years), 68 patients underwent both CXR and chest CT examinations. The percentage of patients with a positive CT score was significantly higher than that obtained on CXR (67.65% > 35.94%, <i>p</i>-value = 0.00258). CT score (21.88 ± 15.77) was significantly (<i>p</i>-value = 0.0014) higher than CXR score (15.06 ± 18.29). CXR and CT revealed prevalent bilateral abnormal findings mainly located in the inferior and middle zones of the lungs. They primarily consisted of peripheral ground-glass opacities and consolidations which predominated on CXR and CT, respectively.https://www.mdpi.com/2379-139X/8/3/126<i>Acinetobacter</i> pneumoniamultidrug resistancechest X-raychest tomographyground-glassconsolidation |
| spellingShingle | Raffaella Capasso Antonio Pinto Nicola Serra Umberto Atripaldi Adele Corcione Giorgio Bocchini Salvatore Guarino Roberta Lieto Gaetano Rea Giacomo Sica Tullio Valente Alert Germ Infections: Chest X-ray and CT Findings in Hospitalized Patients Affected by Multidrug-Resistant <i>Acinetobacter baumannii</i> Pneumonia Tomography <i>Acinetobacter</i> pneumonia multidrug resistance chest X-ray chest tomography ground-glass consolidation |
| title | Alert Germ Infections: Chest X-ray and CT Findings in Hospitalized Patients Affected by Multidrug-Resistant <i>Acinetobacter baumannii</i> Pneumonia |
| title_full | Alert Germ Infections: Chest X-ray and CT Findings in Hospitalized Patients Affected by Multidrug-Resistant <i>Acinetobacter baumannii</i> Pneumonia |
| title_fullStr | Alert Germ Infections: Chest X-ray and CT Findings in Hospitalized Patients Affected by Multidrug-Resistant <i>Acinetobacter baumannii</i> Pneumonia |
| title_full_unstemmed | Alert Germ Infections: Chest X-ray and CT Findings in Hospitalized Patients Affected by Multidrug-Resistant <i>Acinetobacter baumannii</i> Pneumonia |
| title_short | Alert Germ Infections: Chest X-ray and CT Findings in Hospitalized Patients Affected by Multidrug-Resistant <i>Acinetobacter baumannii</i> Pneumonia |
| title_sort | alert germ infections chest x ray and ct findings in hospitalized patients affected by multidrug resistant i acinetobacter baumannii i pneumonia |
| topic | <i>Acinetobacter</i> pneumonia multidrug resistance chest X-ray chest tomography ground-glass consolidation |
| url | https://www.mdpi.com/2379-139X/8/3/126 |
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