A Mycobacterium tuberculosis Effector Targets Mitochondrion, Controls Energy Metabolism, and Limits Cytochrome c Exit

A Mycobacterium tuberculosis Effector Targets Mitochondrion, Controls Energy Metabolism, and Limits Cytochrome c Exit

ABSTRACT Host metabolism reprogramming is a key feature of Mycobacterium tuberculosis (Mtb) infection that enables the survival of this pathogen within phagocytic cells and modulates the immune response facilitating the spread of the tuberculosis disease. Here, we demonstrate that a previously uncha...

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Bibliographic Details
Main Authors: Marianne Martin, Angelique deVisch, Yves-Marie Boudehen, Philippe Barthe, Claude Gutierrez, Obolbek Turapov, Talip Aydogan, Laurène Heriaud, Jerome Gracy, Olivier Neyrolles, Galina V. Mukamolova, François Letourneur, Martin Cohen-Gonsaud
Format: Article
Language:English
Published: American Society for Microbiology 2023-06-01
Series:Microbiology Spectrum
Subjects:
Mycobacterium tuberculosis
apoptosis
metabolism
mitochondria
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01066-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.01066-23

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