Stannous Fluoride Effects on Enamel: A Systematic Review

In recent years there has been a lot of talk about toothpastes with a particular chemical compound: stannous fluoride (SnF<sub>2</sub>). Its presence is currently still highly controversial, as the latter could have negative health effects. The different companies that produce toothpaste...

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Main Authors: Luca Fiorillo, Gabriele Cervino, Alan Scott Herford, Luigi Laino, Marco Cicciù
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Biomimetics
Subjects:
Online Access:https://www.mdpi.com/2313-7673/5/3/41
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author Luca Fiorillo
Gabriele Cervino
Alan Scott Herford
Luigi Laino
Marco Cicciù
author_facet Luca Fiorillo
Gabriele Cervino
Alan Scott Herford
Luigi Laino
Marco Cicciù
author_sort Luca Fiorillo
collection DOAJ
description In recent years there has been a lot of talk about toothpastes with a particular chemical compound: stannous fluoride (SnF<sub>2</sub>). Its presence is currently still highly controversial, as the latter could have negative health effects. The different companies that produce toothpastes express its dosage in ppm. The purpose of this systematic literature review is to analyze all randomized clinical trials in the literature over the last 10 years and to draw clear results on the function of stannous fluoride, for this purpose the authors performed a Mann–Whitney <i>U</i> Test. Materials: The first analysis of the literature produced a number greater than 800 results, subsequently applying the inclusion and exclusion criteria, and following a manual analysis of the results, 26 manuscripts have been obtained. Results: From the results analyzed in this review, it could be shown that stannous fluoride does not present important contraindications, if not those commonly reported for fluorine. A meta-analysis on enamel loss has been conducted, it shows that SnF<sub>2</sub> products provide better results with a <i>p</i> < 0.05 value. Conclusion: This compound could have significant effects in favor of erosion and recalcification of the enamel, on the biofilm formation, gingival inflammation, and in addition, it could be an important aid in the removal of tooth stains and halitosis.
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spelling doaj.art-7641d8a3a58846ad9ada8f7502da24e82023-11-20T11:56:40ZengMDPI AGBiomimetics2313-76732020-08-01534110.3390/biomimetics5030041Stannous Fluoride Effects on Enamel: A Systematic ReviewLuca Fiorillo0Gabriele Cervino1Alan Scott Herford2Luigi Laino3Marco Cicciù4Department of Biomedical and Dental Sciences, Morphological and Functional Images, University of Messina, Policlinico G. Martino, Via Consolare Valeria, 98100 Messina, ItalyDepartment of Biomedical and Dental Sciences, Morphological and Functional Images, University of Messina, Policlinico G. Martino, Via Consolare Valeria, 98100 Messina, ItalyDepartment of Maxillofacial Surgery, Loma Linda University, Loma Linda, CA 92354, USAMultidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania “Luigi Vanvitelli”, 80100 Napoli, ItalyDepartment of Biomedical and Dental Sciences, Morphological and Functional Images, University of Messina, Policlinico G. Martino, Via Consolare Valeria, 98100 Messina, ItalyIn recent years there has been a lot of talk about toothpastes with a particular chemical compound: stannous fluoride (SnF<sub>2</sub>). Its presence is currently still highly controversial, as the latter could have negative health effects. The different companies that produce toothpastes express its dosage in ppm. The purpose of this systematic literature review is to analyze all randomized clinical trials in the literature over the last 10 years and to draw clear results on the function of stannous fluoride, for this purpose the authors performed a Mann–Whitney <i>U</i> Test. Materials: The first analysis of the literature produced a number greater than 800 results, subsequently applying the inclusion and exclusion criteria, and following a manual analysis of the results, 26 manuscripts have been obtained. Results: From the results analyzed in this review, it could be shown that stannous fluoride does not present important contraindications, if not those commonly reported for fluorine. A meta-analysis on enamel loss has been conducted, it shows that SnF<sub>2</sub> products provide better results with a <i>p</i> < 0.05 value. Conclusion: This compound could have significant effects in favor of erosion and recalcification of the enamel, on the biofilm formation, gingival inflammation, and in addition, it could be an important aid in the removal of tooth stains and halitosis.https://www.mdpi.com/2313-7673/5/3/41dentistrystannous fluoridetoothpasteenameloral healthoral hygiene
spellingShingle Luca Fiorillo
Gabriele Cervino
Alan Scott Herford
Luigi Laino
Marco Cicciù
Stannous Fluoride Effects on Enamel: A Systematic Review
Biomimetics
dentistry
stannous fluoride
toothpaste
enamel
oral health
oral hygiene
title Stannous Fluoride Effects on Enamel: A Systematic Review
title_full Stannous Fluoride Effects on Enamel: A Systematic Review
title_fullStr Stannous Fluoride Effects on Enamel: A Systematic Review
title_full_unstemmed Stannous Fluoride Effects on Enamel: A Systematic Review
title_short Stannous Fluoride Effects on Enamel: A Systematic Review
title_sort stannous fluoride effects on enamel a systematic review
topic dentistry
stannous fluoride
toothpaste
enamel
oral health
oral hygiene
url https://www.mdpi.com/2313-7673/5/3/41
work_keys_str_mv AT lucafiorillo stannousfluorideeffectsonenamelasystematicreview
AT gabrielecervino stannousfluorideeffectsonenamelasystematicreview
AT alanscottherford stannousfluorideeffectsonenamelasystematicreview
AT luigilaino stannousfluorideeffectsonenamelasystematicreview
AT marcocicciu stannousfluorideeffectsonenamelasystematicreview