Minimum detectable spinal cord atrophy with automatic segmentation: Investigations using an open-access dataset of healthy participants

Spinal cord atrophy is a well-known biomarker in multiple sclerosis (MS) and other diseases. It is measured by segmenting the spinal cord on an MRI image and computing the average cross-sectional area (CSA) over a few slices. Introduced about 25 years ago, this procedure is highly sensitive to the q...

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Bibliographic Details
Main Authors: Paul Bautin, Julien Cohen-Adad
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:NeuroImage: Clinical
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S221315822100293X