Multiparametric chemical exchange saturation transfer MRI detects metabolic changes in breast cancer following immunotherapy

Multiparametric chemical exchange saturation transfer MRI detects metabolic changes in breast cancer following immunotherapy

Abstract Background With metabolic alterations of the tumor microenvironment (TME) contributing to cancer progression, metastatic spread and response to targeted therapies, non-invasive and repetitive imaging of tumor metabolism is of major importance. The purpose of this study was to investigate wh...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Emily Hoffmann, Daniel Schache, Carsten Höltke, Jens Soltwisch, Stephan Niland, Tobias Krähling, Klaus Bergander, Martin Grewer, Christiane Geyer, Linda Groeneweg, Johannes A. Eble, Thomas Vogl, Johannes Roth, Walter Heindel, Bastian Maus, Anne Helfen, Cornelius Faber, Moritz Wildgruber, Mirjam Gerwing, Verena Hoerr
Format: Artikel
Sprache:English
Veröffentlicht: BMC 2023-08-01
Schriftenreihe:Journal of Translational Medicine
Schlagworte:
CEST
Metabolism
Tumor malignancy
Immune checkpoint inhibition
MRI
Online Zugang:https://doi.org/10.1186/s12967-023-04451-6

Online

https://doi.org/10.1186/s12967-023-04451-6

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