Electrical Stimulation Therapy and HA/TCP Composite Scaffolds Modulate the Wnt Pathways in Bone Regeneration of Critical-Sized Defects

Electrical Stimulation Therapy and HA/TCP Composite Scaffolds Modulate the Wnt Pathways in Bone Regeneration of Critical-Sized Defects

Critical bone defects are the most difficult challenges in the area of tissue repair. Polycaprolactone (PCL) scaffolds, associated with hydroxyapatite (HA) and tricalcium phosphate (TCP), are reported to have an enhanced bioactivity. Moreover, the use of electrical stimulation (ES) has overcome the...

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Bibliographic Details
Main Authors: Júlia Venturini Helaehil, Luiza Venturini Helaehil, Laryssa Fernanda Alves, Boyang Huang, Milton Santamaria-Jr, Paulo Bartolo, Guilherme Ferreira Caetano
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Bioengineering
Subjects:
bioprinting
electrical stimulation
microcurrent
mineralization
osteogenesis
tissue engineering
Online Access:https://www.mdpi.com/2306-5354/10/1/75

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