Neonatal Thrombocytopenia: Diagnostic Approach and Platelet Transfusion Guideline
Neonatal thrombocytopenia, defined as platelet counts of less than 150,000/µL, is a frequent hematologic abnormality in neonatal period. Differential diagnosis of neonatal thrombocytopenia may be challenging to pediatric hematologists and neonatologists because neonatal thrombocytopenia is associate...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
The Korean Society of Pediatric Hematology-Oncology
2019-10-01
|
| Series: | Clinical Pediatric Hematology-Oncology |
| Subjects: | |
| Online Access: | https://doi.org/10.15264/cpho.2019.26.2.67 |
| _version_ | 1818409114327318528 |
|---|---|
| author | Ji Sook Kim Ji Yoon Kim |
| author_facet | Ji Sook Kim Ji Yoon Kim |
| author_sort | Ji Sook Kim |
| collection | DOAJ |
| description | Neonatal thrombocytopenia, defined as platelet counts of less than 150,000/µL, is a frequent hematologic abnormality in neonatal period. Differential diagnosis of neonatal thrombocytopenia may be challenging to pediatric hematologists and neonatologists because neonatal thrombocytopenia is associated with diverse maternal or neonatal clinical conditions. An accurate diagnosis for neonatal thrombocytopenia will lead to appropriate evaluation and management. Platelet transfusion is the primary management of neonatal thrombocytopenia. Most thrombocytopenic newborns received platelet concentrates to prevent major hemorrhage or treat ongoing bleeding according to institutional policy. However, scientific evidences for benefit and consistent guideline for platelet transfusion in neonates are lacking, further investigation to establish the standard recommendation for platelet transfusion is needed. This article reviewed the diagnostic approach and current guideline for platelet transfusion management for neonatal thrombocytopenia. |
| first_indexed | 2024-12-14T09:54:29Z |
| format | Article |
| id | doaj.art-764748246ee24ca1bd71f829d4767c11 |
| institution | Directory Open Access Journal |
| issn | 2233-5250 |
| language | English |
| last_indexed | 2024-12-14T09:54:29Z |
| publishDate | 2019-10-01 |
| publisher | The Korean Society of Pediatric Hematology-Oncology |
| record_format | Article |
| series | Clinical Pediatric Hematology-Oncology |
| spelling | doaj.art-764748246ee24ca1bd71f829d4767c112022-12-21T23:07:26ZengThe Korean Society of Pediatric Hematology-OncologyClinical Pediatric Hematology-Oncology2233-52502019-10-01262677610.15264/cpho.2019.26.2.67cpho.2019.26.2.67Neonatal Thrombocytopenia: Diagnostic Approach and Platelet Transfusion GuidelineJi Sook Kim0Ji Yoon Kim1Department of Pediatrics, School of Medicine, Kyungpook National University, Daegu, KoreaDepartment of Pediatrics, School of Medicine, Kyungpook National University, Daegu, KoreaNeonatal thrombocytopenia, defined as platelet counts of less than 150,000/µL, is a frequent hematologic abnormality in neonatal period. Differential diagnosis of neonatal thrombocytopenia may be challenging to pediatric hematologists and neonatologists because neonatal thrombocytopenia is associated with diverse maternal or neonatal clinical conditions. An accurate diagnosis for neonatal thrombocytopenia will lead to appropriate evaluation and management. Platelet transfusion is the primary management of neonatal thrombocytopenia. Most thrombocytopenic newborns received platelet concentrates to prevent major hemorrhage or treat ongoing bleeding according to institutional policy. However, scientific evidences for benefit and consistent guideline for platelet transfusion in neonates are lacking, further investigation to establish the standard recommendation for platelet transfusion is needed. This article reviewed the diagnostic approach and current guideline for platelet transfusion management for neonatal thrombocytopenia.https://doi.org/10.15264/cpho.2019.26.2.67neonateinfantthrombocytopeniaplateletstransfusion |
| spellingShingle | Ji Sook Kim Ji Yoon Kim Neonatal Thrombocytopenia: Diagnostic Approach and Platelet Transfusion Guideline Clinical Pediatric Hematology-Oncology neonate infant thrombocytopenia platelets transfusion |
| title | Neonatal Thrombocytopenia: Diagnostic Approach and Platelet Transfusion Guideline |
| title_full | Neonatal Thrombocytopenia: Diagnostic Approach and Platelet Transfusion Guideline |
| title_fullStr | Neonatal Thrombocytopenia: Diagnostic Approach and Platelet Transfusion Guideline |
| title_full_unstemmed | Neonatal Thrombocytopenia: Diagnostic Approach and Platelet Transfusion Guideline |
| title_short | Neonatal Thrombocytopenia: Diagnostic Approach and Platelet Transfusion Guideline |
| title_sort | neonatal thrombocytopenia diagnostic approach and platelet transfusion guideline |
| topic | neonate infant thrombocytopenia platelets transfusion |
| url | https://doi.org/10.15264/cpho.2019.26.2.67 |
| work_keys_str_mv | AT jisookkim neonatalthrombocytopeniadiagnosticapproachandplatelettransfusionguideline AT jiyoonkim neonatalthrombocytopeniadiagnosticapproachandplatelettransfusionguideline |