The Research Domain Criteria framework: transitioning from dimensional systems to integrating neuroscience and psychopathology

Although recent research in neuroscience and genetics is providing new insights into the etiology of psychiatric disorders, progress in treatment development has been hindered by reliance on diagnostic categories that are based primarily on presenting signs and symptoms. The NIMH Research Domain Cri...

Full description

Bibliographic Details
Main Authors: Samet Kose, Mesut Cetin
Format: Article
Language:English
Published: AVES 2017-01-01
Series:Psychiatry and Clinical Psychopharmacology
Subjects:
Online Access:http://dx.doi.org/10.1080/24750573.2017.1293255
_version_ 1797917397166850048
author Samet Kose
Mesut Cetin
author_facet Samet Kose
Mesut Cetin
author_sort Samet Kose
collection DOAJ
description Although recent research in neuroscience and genetics is providing new insights into the etiology of psychiatric disorders, progress in treatment development has been hindered by reliance on diagnostic categories that are based primarily on presenting signs and symptoms. The NIMH Research Domain Criteria (RDoC) framework seeks to provide a neuroscience-based nosological background for future research on psychopathology, categorizing individuals for research purposes using a dimensional approach that benefit from significant progress in modern neuroscience. These scientific advances combined with new approaches to classification can inform the development of novel, circuit-based interventions and the personalization of treatments available. In this editorial, we describe the RDoC framework compared with Diagnostic and Statistical Manual/International Classification of Disease systems and highlight some of the emerging progress in RDoC-based research that is consistent with these developments.
first_indexed 2024-04-10T13:12:31Z
format Article
id doaj.art-765150cae3944530be46c53fd094f908
institution Directory Open Access Journal
issn 2475-0573
2475-0581
language English
last_indexed 2024-04-10T13:12:31Z
publishDate 2017-01-01
publisher AVES
record_format Article
series Psychiatry and Clinical Psychopharmacology
spelling doaj.art-765150cae3944530be46c53fd094f9082023-02-15T16:12:32ZengAVESPsychiatry and Clinical Psychopharmacology2475-05732475-05812017-01-012711510.1080/24750573.2017.12932551293255The Research Domain Criteria framework: transitioning from dimensional systems to integrating neuroscience and psychopathologySamet Kose0Mesut Cetin1MD, PhD, Assoc. Prof. of PsychiatryPsychiatry & Clinical Psychopharmacology and Journal of Mood DisordersAlthough recent research in neuroscience and genetics is providing new insights into the etiology of psychiatric disorders, progress in treatment development has been hindered by reliance on diagnostic categories that are based primarily on presenting signs and symptoms. The NIMH Research Domain Criteria (RDoC) framework seeks to provide a neuroscience-based nosological background for future research on psychopathology, categorizing individuals for research purposes using a dimensional approach that benefit from significant progress in modern neuroscience. These scientific advances combined with new approaches to classification can inform the development of novel, circuit-based interventions and the personalization of treatments available. In this editorial, we describe the RDoC framework compared with Diagnostic and Statistical Manual/International Classification of Disease systems and highlight some of the emerging progress in RDoC-based research that is consistent with these developments.http://dx.doi.org/10.1080/24750573.2017.1293255RDoCneurosciencepsychiatric diagnosispsychiatric treatment
spellingShingle Samet Kose
Mesut Cetin
The Research Domain Criteria framework: transitioning from dimensional systems to integrating neuroscience and psychopathology
Psychiatry and Clinical Psychopharmacology
RDoC
neuroscience
psychiatric diagnosis
psychiatric treatment
title The Research Domain Criteria framework: transitioning from dimensional systems to integrating neuroscience and psychopathology
title_full The Research Domain Criteria framework: transitioning from dimensional systems to integrating neuroscience and psychopathology
title_fullStr The Research Domain Criteria framework: transitioning from dimensional systems to integrating neuroscience and psychopathology
title_full_unstemmed The Research Domain Criteria framework: transitioning from dimensional systems to integrating neuroscience and psychopathology
title_short The Research Domain Criteria framework: transitioning from dimensional systems to integrating neuroscience and psychopathology
title_sort research domain criteria framework transitioning from dimensional systems to integrating neuroscience and psychopathology
topic RDoC
neuroscience
psychiatric diagnosis
psychiatric treatment
url http://dx.doi.org/10.1080/24750573.2017.1293255
work_keys_str_mv AT sametkose theresearchdomaincriteriaframeworktransitioningfromdimensionalsystemstointegratingneuroscienceandpsychopathology
AT mesutcetin theresearchdomaincriteriaframeworktransitioningfromdimensionalsystemstointegratingneuroscienceandpsychopathology
AT sametkose researchdomaincriteriaframeworktransitioningfromdimensionalsystemstointegratingneuroscienceandpsychopathology
AT mesutcetin researchdomaincriteriaframeworktransitioningfromdimensionalsystemstointegratingneuroscienceandpsychopathology