Formulation and characterization of antibacterial orthodontic adhesive
ABSTRACT Objective: The objective of this study was to formulate experimental orthodontic bracket adhesives and test their mechanical properties, fluoride release and antibacterial activity. Methods: Four experimental antibacterial orthodontic bracket adhesives were prepared with different compos...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Dental Press Editora
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| Series: | Dental Press Journal of Orthodontics |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2176-94512019000400073&lng=en&tlng=en |
| _version_ | 1818359357432135680 |
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| author | Jefferson Twomley Qingzhao Yu Richard Ballard Paul Armbruster Xiaoming Xu |
| author_facet | Jefferson Twomley Qingzhao Yu Richard Ballard Paul Armbruster Xiaoming Xu |
| author_sort | Jefferson Twomley |
| collection | DOAJ |
| description | ABSTRACT Objective: The objective of this study was to formulate experimental orthodontic bracket adhesives and test their mechanical properties, fluoride release and antibacterial activity. Methods: Four experimental antibacterial orthodontic bracket adhesives were prepared with different compositions of synthesized antibacterial monomers replacing total 5% of dental monomers in the control Transbond XT (3M): 5%C11, 3.5%C11+1.5%C2, 5%C16, and 3.5%C16+1.5%C2. Transbond XT alone was used as control. These groups were used to bond premolar brackets to extracted premolars. Shear bond strength (SBS) was tested using an Instron machine. For antibacterial test, disk specimens (10mm diameter, 1mm thick, n=4) were fabricated and incubated with cultures of cariogenic Streptococcus mutans for 48h, and following gentle sonication, S. mutans biofilms in colony-forming-units (CFU) on the disks were enumerated by plating on agar medium. The data were analyzed using ANOVA and Tukey test (α=0.05). Results: All experimental groups had similar shear bond strength (no significant difference) to the control. All experimental groups showed significant inhibitory effect against S. mutans biofilm formation, when compared to the control, but there was no significant difference between experimental groups. Conclusion: Antibacterial orthodontic adhesive can be fabricated to have similar mechanical properties but better caries-inhibitory effect than current adhesive. |
| first_indexed | 2024-12-13T20:43:37Z |
| format | Article |
| id | doaj.art-7653ad8d613f42a0ae3f678ead6e0305 |
| institution | Directory Open Access Journal |
| issn | 2177-6709 |
| language | English |
| last_indexed | 2024-12-13T20:43:37Z |
| publisher | Dental Press Editora |
| record_format | Article |
| series | Dental Press Journal of Orthodontics |
| spelling | doaj.art-7653ad8d613f42a0ae3f678ead6e03052022-12-21T23:32:04ZengDental Press EditoraDental Press Journal of Orthodontics2177-6709244737910.1590/2177-6709.24.4.073-079.oarS2176-94512019000400073Formulation and characterization of antibacterial orthodontic adhesiveJefferson TwomleyQingzhao YuRichard BallardPaul ArmbrusterXiaoming XuABSTRACT Objective: The objective of this study was to formulate experimental orthodontic bracket adhesives and test their mechanical properties, fluoride release and antibacterial activity. Methods: Four experimental antibacterial orthodontic bracket adhesives were prepared with different compositions of synthesized antibacterial monomers replacing total 5% of dental monomers in the control Transbond XT (3M): 5%C11, 3.5%C11+1.5%C2, 5%C16, and 3.5%C16+1.5%C2. Transbond XT alone was used as control. These groups were used to bond premolar brackets to extracted premolars. Shear bond strength (SBS) was tested using an Instron machine. For antibacterial test, disk specimens (10mm diameter, 1mm thick, n=4) were fabricated and incubated with cultures of cariogenic Streptococcus mutans for 48h, and following gentle sonication, S. mutans biofilms in colony-forming-units (CFU) on the disks were enumerated by plating on agar medium. The data were analyzed using ANOVA and Tukey test (α=0.05). Results: All experimental groups had similar shear bond strength (no significant difference) to the control. All experimental groups showed significant inhibitory effect against S. mutans biofilm formation, when compared to the control, but there was no significant difference between experimental groups. Conclusion: Antibacterial orthodontic adhesive can be fabricated to have similar mechanical properties but better caries-inhibitory effect than current adhesive.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2176-94512019000400073&lng=en&tlng=enAdesivoLiberação de flúorAntibacterianoOrtodontia |
| spellingShingle | Jefferson Twomley Qingzhao Yu Richard Ballard Paul Armbruster Xiaoming Xu Formulation and characterization of antibacterial orthodontic adhesive Dental Press Journal of Orthodontics Adesivo Liberação de flúor Antibacteriano Ortodontia |
| title | Formulation and characterization of antibacterial orthodontic adhesive |
| title_full | Formulation and characterization of antibacterial orthodontic adhesive |
| title_fullStr | Formulation and characterization of antibacterial orthodontic adhesive |
| title_full_unstemmed | Formulation and characterization of antibacterial orthodontic adhesive |
| title_short | Formulation and characterization of antibacterial orthodontic adhesive |
| title_sort | formulation and characterization of antibacterial orthodontic adhesive |
| topic | Adesivo Liberação de flúor Antibacteriano Ortodontia |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2176-94512019000400073&lng=en&tlng=en |
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