Seroprevalence of contagious bovine pleuropneumonia (CBPP) in cattle from Karamoja region, North-eastern Uganda
Abstract Background Contagious bovine pleuropneumonia [CBPP] is a transboundary animal disease of cattle caused by Mycoplasma mycoides subsp. mycoides [Mmm]. CBPP causes severe economic losses to livestock producers in sub-Saharan Africa mainly due to high mortality, morbidity, reduction in producti...
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| Format: | Article |
| Language: | English |
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BMC
2024-03-01
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| Series: | BMC Veterinary Research |
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| Online Access: | https://doi.org/10.1186/s12917-024-03938-8 |
| _version_ | 1827321364829175808 |
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| author | Robert Tweyongyere Joseph Nkamwesiga Patrick Etiang Israel Mugezi Henry Wamala Auther Tamale Wasswa Maureen Kamusiime Solomon Ainebyoona Harriet Abizera Frank Norbert Mwiine Dennis Muhanguzi |
| author_facet | Robert Tweyongyere Joseph Nkamwesiga Patrick Etiang Israel Mugezi Henry Wamala Auther Tamale Wasswa Maureen Kamusiime Solomon Ainebyoona Harriet Abizera Frank Norbert Mwiine Dennis Muhanguzi |
| author_sort | Robert Tweyongyere |
| collection | DOAJ |
| description | Abstract Background Contagious bovine pleuropneumonia [CBPP] is a transboundary animal disease of cattle caused by Mycoplasma mycoides subsp. mycoides [Mmm]. CBPP causes severe economic losses to livestock producers in sub-Saharan Africa mainly due to high mortality, morbidity, reduction in productivity as well as livestock trade restrictions. This study aimed at determining seroprevalence of Mmm in cattle from Karamoja region, north-eastern Uganda; data that are required to design and implement risk based CBPP control program. Methods We randomly collected blood samples from 2,300 cattle spread across Karamoja region. Serum was extracted and screened for antibodies against Mycoplasma mycoides subsp. mycoides [Mmm] using the competitive enzyme linked immunosorbent assay [cELISA]. Results A quarter [25.4%; 95% CI: 23.7–27.3] of the screened cattle [n = 2,300] were sero-positive for Mmm. Amudat and Kaabong districts recorded the lowest [12.3%] and highest [30.7%] Mmm seroprevalence respectively. Increasing age, overnight stay in cattle kraals and location [certain districts, villages, herds and sub counties] of the cattle herds, the factors that promote animal commingling, were the most significant risk factors of seroconversion with Mmm. Conclusion Results from this study indicated a higher seroprevalence of Mmm in Karamoja region cattle herds. This could be due to the increased frequency of CBPP outbreaks in recent years. To be effective, CBPP vaccination programs should target high risk herds along the international borders and other hotspot areas [e.g., parishes or sub counties] where cattle commingling is high. |
| first_indexed | 2024-04-25T01:06:02Z |
| format | Article |
| id | doaj.art-765839052c704276b0ff8f1358714029 |
| institution | Directory Open Access Journal |
| issn | 1746-6148 |
| language | English |
| last_indexed | 2024-04-25T01:06:02Z |
| publishDate | 2024-03-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Veterinary Research |
| spelling | doaj.art-765839052c704276b0ff8f13587140292024-03-10T12:15:08ZengBMCBMC Veterinary Research1746-61482024-03-012011910.1186/s12917-024-03938-8Seroprevalence of contagious bovine pleuropneumonia (CBPP) in cattle from Karamoja region, North-eastern UgandaRobert Tweyongyere0Joseph Nkamwesiga1Patrick Etiang2Israel Mugezi3Henry Wamala4Auther Tamale Wasswa5Maureen Kamusiime6Solomon Ainebyoona7Harriet Abizera8Frank Norbert Mwiine9Dennis Muhanguzi10College of Veterinary Medicine Animal Resources and Biosecurity, Makerere UniversityCollege of Veterinary Medicine Animal Resources and Biosecurity, Makerere UniversityFaculty of Agriculture and Animal Sciences, Busitema UniversityDepartment of Animal Health, Ministry of Agriculture Animal Industry and FisheriesMercy Corps UgandaCollege of Veterinary Medicine Animal Resources and Biosecurity, Makerere UniversityMercy Corps UgandaCollege of Veterinary Medicine Animal Resources and Biosecurity, Makerere UniversityCollege of Veterinary Medicine Animal Resources and Biosecurity, Makerere UniversityCollege of Veterinary Medicine Animal Resources and Biosecurity, Makerere UniversityCollege of Veterinary Medicine Animal Resources and Biosecurity, Makerere UniversityAbstract Background Contagious bovine pleuropneumonia [CBPP] is a transboundary animal disease of cattle caused by Mycoplasma mycoides subsp. mycoides [Mmm]. CBPP causes severe economic losses to livestock producers in sub-Saharan Africa mainly due to high mortality, morbidity, reduction in productivity as well as livestock trade restrictions. This study aimed at determining seroprevalence of Mmm in cattle from Karamoja region, north-eastern Uganda; data that are required to design and implement risk based CBPP control program. Methods We randomly collected blood samples from 2,300 cattle spread across Karamoja region. Serum was extracted and screened for antibodies against Mycoplasma mycoides subsp. mycoides [Mmm] using the competitive enzyme linked immunosorbent assay [cELISA]. Results A quarter [25.4%; 95% CI: 23.7–27.3] of the screened cattle [n = 2,300] were sero-positive for Mmm. Amudat and Kaabong districts recorded the lowest [12.3%] and highest [30.7%] Mmm seroprevalence respectively. Increasing age, overnight stay in cattle kraals and location [certain districts, villages, herds and sub counties] of the cattle herds, the factors that promote animal commingling, were the most significant risk factors of seroconversion with Mmm. Conclusion Results from this study indicated a higher seroprevalence of Mmm in Karamoja region cattle herds. This could be due to the increased frequency of CBPP outbreaks in recent years. To be effective, CBPP vaccination programs should target high risk herds along the international borders and other hotspot areas [e.g., parishes or sub counties] where cattle commingling is high.https://doi.org/10.1186/s12917-024-03938-8Karamoja regionUgandaSeroprevalenceCBPPcELISACattle |
| spellingShingle | Robert Tweyongyere Joseph Nkamwesiga Patrick Etiang Israel Mugezi Henry Wamala Auther Tamale Wasswa Maureen Kamusiime Solomon Ainebyoona Harriet Abizera Frank Norbert Mwiine Dennis Muhanguzi Seroprevalence of contagious bovine pleuropneumonia (CBPP) in cattle from Karamoja region, North-eastern Uganda BMC Veterinary Research Karamoja region Uganda Seroprevalence CBPP cELISA Cattle |
| title | Seroprevalence of contagious bovine pleuropneumonia (CBPP) in cattle from Karamoja region, North-eastern Uganda |
| title_full | Seroprevalence of contagious bovine pleuropneumonia (CBPP) in cattle from Karamoja region, North-eastern Uganda |
| title_fullStr | Seroprevalence of contagious bovine pleuropneumonia (CBPP) in cattle from Karamoja region, North-eastern Uganda |
| title_full_unstemmed | Seroprevalence of contagious bovine pleuropneumonia (CBPP) in cattle from Karamoja region, North-eastern Uganda |
| title_short | Seroprevalence of contagious bovine pleuropneumonia (CBPP) in cattle from Karamoja region, North-eastern Uganda |
| title_sort | seroprevalence of contagious bovine pleuropneumonia cbpp in cattle from karamoja region north eastern uganda |
| topic | Karamoja region Uganda Seroprevalence CBPP cELISA Cattle |
| url | https://doi.org/10.1186/s12917-024-03938-8 |
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