Can Burn Injury Cause Thrombotic Thrombocytopenic Purpura?
Thrombotic thrombocytopenic purpura (TTP) is characterized by the pentad of microangiopathic hemolytic anemia, uremia, thrombocytopenia, neurological symptoms, and fever. It can be a fatal emergency if early diagnosis and appropriate evaluation are not performed. TTP is associated with an acquired o...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
KARE Publishing
2019-07-01
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| Series: | Southern Clinics of Istanbul Eurasia |
| Subjects: | |
| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=scie&un=SCIE-74046 |
| _version_ | 1797912362557112320 |
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| author | Mehmet Akif Öztürk Nisa Babacanlar Cafer Akkoz Ali Özdemir |
| author_facet | Mehmet Akif Öztürk Nisa Babacanlar Cafer Akkoz Ali Özdemir |
| author_sort | Mehmet Akif Öztürk |
| collection | DOAJ |
| description | Thrombotic thrombocytopenic purpura (TTP) is characterized by the pentad of microangiopathic hemolytic anemia, uremia, thrombocytopenia, neurological symptoms, and fever. It can be a fatal emergency if early diagnosis and appropriate evaluation are not performed. TTP is associated with an acquired or congenital deficiency of the von Willebrand factor-cleaving metalloprotease, ADAMTS13. It can be triggered by many diseases or drugs. Plasma exchange, which is an urgent treatment modality, can be effective in cases of TTP. Presently described is the case of a 35-year-old man with a diagnosis of TTP that developed after a burn injury. The underlying mechanism of TTP development after a burn is still unknown. Clinicians should pay attention to neurological symptoms and thrombocytopenia after burn accidents and must be alert to this life-threatening situation. |
| first_indexed | 2024-04-10T11:54:53Z |
| format | Article |
| id | doaj.art-765d6c001df6433c91619f1363c0e573 |
| institution | Directory Open Access Journal |
| issn | 2587-0998 |
| language | English |
| last_indexed | 2024-04-10T11:54:53Z |
| publishDate | 2019-07-01 |
| publisher | KARE Publishing |
| record_format | Article |
| series | Southern Clinics of Istanbul Eurasia |
| spelling | doaj.art-765d6c001df6433c91619f1363c0e5732023-02-15T16:16:51ZengKARE PublishingSouthern Clinics of Istanbul Eurasia2587-09982019-07-0130217517710.14744/scie.2019.74046SCIE-74046Can Burn Injury Cause Thrombotic Thrombocytopenic Purpura?Mehmet Akif Öztürk0Nisa Babacanlar1Cafer Akkoz2Ali Özdemir3Department of Internal Medicine, Fatih Sultan Mehmet Training and Research Hospital, İstanbul, TurkeyDepartment of Internal Medicine, Fatih Sultan Mehmet Training and Research Hospital, İstanbul, TurkeyDepartment of Internal Medicine, Fatih Sultan Mehmet Training and Research Hospital, İstanbul, TurkeyDepartment of Internal Medicine, Fatih Sultan Mehmet Training and Research Hospital, İstanbul, TurkeyThrombotic thrombocytopenic purpura (TTP) is characterized by the pentad of microangiopathic hemolytic anemia, uremia, thrombocytopenia, neurological symptoms, and fever. It can be a fatal emergency if early diagnosis and appropriate evaluation are not performed. TTP is associated with an acquired or congenital deficiency of the von Willebrand factor-cleaving metalloprotease, ADAMTS13. It can be triggered by many diseases or drugs. Plasma exchange, which is an urgent treatment modality, can be effective in cases of TTP. Presently described is the case of a 35-year-old man with a diagnosis of TTP that developed after a burn injury. The underlying mechanism of TTP development after a burn is still unknown. Clinicians should pay attention to neurological symptoms and thrombocytopenia after burn accidents and must be alert to this life-threatening situation.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=scie&un=SCIE-74046anemiaburnthrombotic thrombocytopenic purpura. |
| spellingShingle | Mehmet Akif Öztürk Nisa Babacanlar Cafer Akkoz Ali Özdemir Can Burn Injury Cause Thrombotic Thrombocytopenic Purpura? Southern Clinics of Istanbul Eurasia anemia burn thrombotic thrombocytopenic purpura. |
| title | Can Burn Injury Cause Thrombotic Thrombocytopenic Purpura? |
| title_full | Can Burn Injury Cause Thrombotic Thrombocytopenic Purpura? |
| title_fullStr | Can Burn Injury Cause Thrombotic Thrombocytopenic Purpura? |
| title_full_unstemmed | Can Burn Injury Cause Thrombotic Thrombocytopenic Purpura? |
| title_short | Can Burn Injury Cause Thrombotic Thrombocytopenic Purpura? |
| title_sort | can burn injury cause thrombotic thrombocytopenic purpura |
| topic | anemia burn thrombotic thrombocytopenic purpura. |
| url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=scie&un=SCIE-74046 |
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