Evidence of exposure and human seroconversion during an outbreak of avian influenza A(H5N1) among poultry in Cameroon
ABSTRACTFrom May 2016 to March 2017, 22 poultry outbreaks of avian influenza A(H5N1) were reported in Cameroon, mainly in poultry farms and live bird markets. No human cases were reported. In this study, we sought to describe the 2016 A(H5N1) outbreak strain and to investigate the risk of infection...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2019-01-01
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| Series: | Emerging Microbes and Infections |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/22221751.2018.1564631 |
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| author | Chavely Gwladys Monamele Phalla Y. Erik Albert Karlsson Marie-Astrid Vernet Abel Wade Marie-Claire Assoumou Okomo Aristide Stéphane Abah Abah Sokhoun Yann Georges Alain Mballa Etoundi Njankouo Ripa Mohamadou Jean-Marc Feussom Sreyviseth Horm Paul Francis Horwood Sowath Ly Richard Njouom Philippe Dussart |
| author_facet | Chavely Gwladys Monamele Phalla Y. Erik Albert Karlsson Marie-Astrid Vernet Abel Wade Marie-Claire Assoumou Okomo Aristide Stéphane Abah Abah Sokhoun Yann Georges Alain Mballa Etoundi Njankouo Ripa Mohamadou Jean-Marc Feussom Sreyviseth Horm Paul Francis Horwood Sowath Ly Richard Njouom Philippe Dussart |
| author_sort | Chavely Gwladys Monamele |
| collection | DOAJ |
| description | ABSTRACTFrom May 2016 to March 2017, 22 poultry outbreaks of avian influenza A(H5N1) were reported in Cameroon, mainly in poultry farms and live bird markets. No human cases were reported. In this study, we sought to describe the 2016 A(H5N1) outbreak strain and to investigate the risk of infection in exposed individuals. We find that highly pathogenic influenza subtype A(H5N1), clade 2.3.2.1c from Cameroon is closely related phylogenetically and antigenically to strains isolated in central and western Africa at the time. No molecular markers of increased human transmissibility were noted; however, seroconversion was detected in two poultry workers (1.5% of total screened). Therefore, the continued outbreaks of avian influenza in poultry and the risk of zoonotic human infection highlight the crucial need for continued and vigilant influenza surveillance and research in Africa, especially in areas of high poultry trade, such as Cameroon. |
| first_indexed | 2024-03-08T21:59:01Z |
| format | Article |
| id | doaj.art-7665983434e54560814a97a0226634ca |
| institution | Directory Open Access Journal |
| issn | 2222-1751 |
| language | English |
| last_indexed | 2024-03-08T21:59:01Z |
| publishDate | 2019-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Emerging Microbes and Infections |
| spelling | doaj.art-7665983434e54560814a97a0226634ca2023-12-19T16:09:57ZengTaylor & Francis GroupEmerging Microbes and Infections2222-17512019-01-018118619610.1080/22221751.2018.1564631Evidence of exposure and human seroconversion during an outbreak of avian influenza A(H5N1) among poultry in CameroonChavely Gwladys Monamele0Phalla Y.1Erik Albert Karlsson2Marie-Astrid Vernet3Abel Wade4Marie-Claire Assoumou Okomo5Aristide Stéphane Abah Abah6Sokhoun Yann7Georges Alain Mballa Etoundi8Njankouo Ripa Mohamadou9Jean-Marc Feussom10Sreyviseth Horm11Paul Francis Horwood12Sowath Ly13Richard Njouom14Philippe Dussart15Virology Department, Centre Pasteur du Cameroun, Institut Pasteur International Network, Yaoundé, CameroonVirology Unit, Institut Pasteur du Cambodge, Institut Pasteur International Network, Phnom Penh, CambodiaVirology Unit, Institut Pasteur du Cambodge, Institut Pasteur International Network, Phnom Penh, CambodiaVirology Department, Centre Pasteur du Cameroun, Institut Pasteur International Network, Yaoundé, CameroonMinistry of Livestock, Fisheries and Animal Industries, Yaoundé, CameroonNational Laboratory of Public Health, Yaoundé, CameroonMinistry of Public Health, Yaoundé, CameroonVirology Unit, Institut Pasteur du Cambodge, Institut Pasteur International Network, Phnom Penh, CambodiaMinistry of Public Health, Yaoundé, CameroonVirology Department, Centre Pasteur du Cameroun, Institut Pasteur International Network, Yaoundé, CameroonMinistry of Livestock, Fisheries and Animal Industries, Yaoundé, CameroonVirology Unit, Institut Pasteur du Cambodge, Institut Pasteur International Network, Phnom Penh, CambodiaVirology Unit, Institut Pasteur du Cambodge, Institut Pasteur International Network, Phnom Penh, CambodiaEpidemiology and Public Health Unit, Institut Pasteur du Cambodge, Institut Pasteur International Network, Phnom Penh, CambodiaVirology Department, Centre Pasteur du Cameroun, Institut Pasteur International Network, Yaoundé, CameroonVirology Unit, Institut Pasteur du Cambodge, Institut Pasteur International Network, Phnom Penh, CambodiaABSTRACTFrom May 2016 to March 2017, 22 poultry outbreaks of avian influenza A(H5N1) were reported in Cameroon, mainly in poultry farms and live bird markets. No human cases were reported. In this study, we sought to describe the 2016 A(H5N1) outbreak strain and to investigate the risk of infection in exposed individuals. We find that highly pathogenic influenza subtype A(H5N1), clade 2.3.2.1c from Cameroon is closely related phylogenetically and antigenically to strains isolated in central and western Africa at the time. No molecular markers of increased human transmissibility were noted; however, seroconversion was detected in two poultry workers (1.5% of total screened). Therefore, the continued outbreaks of avian influenza in poultry and the risk of zoonotic human infection highlight the crucial need for continued and vigilant influenza surveillance and research in Africa, especially in areas of high poultry trade, such as Cameroon.https://www.tandfonline.com/doi/10.1080/22221751.2018.1564631Avian influenzaH5N1AfricaCameroonZoonosessurveillance |
| spellingShingle | Chavely Gwladys Monamele Phalla Y. Erik Albert Karlsson Marie-Astrid Vernet Abel Wade Marie-Claire Assoumou Okomo Aristide Stéphane Abah Abah Sokhoun Yann Georges Alain Mballa Etoundi Njankouo Ripa Mohamadou Jean-Marc Feussom Sreyviseth Horm Paul Francis Horwood Sowath Ly Richard Njouom Philippe Dussart Evidence of exposure and human seroconversion during an outbreak of avian influenza A(H5N1) among poultry in Cameroon Emerging Microbes and Infections Avian influenza H5N1 Africa Cameroon Zoonoses surveillance |
| title | Evidence of exposure and human seroconversion during an outbreak of avian influenza A(H5N1) among poultry in Cameroon |
| title_full | Evidence of exposure and human seroconversion during an outbreak of avian influenza A(H5N1) among poultry in Cameroon |
| title_fullStr | Evidence of exposure and human seroconversion during an outbreak of avian influenza A(H5N1) among poultry in Cameroon |
| title_full_unstemmed | Evidence of exposure and human seroconversion during an outbreak of avian influenza A(H5N1) among poultry in Cameroon |
| title_short | Evidence of exposure and human seroconversion during an outbreak of avian influenza A(H5N1) among poultry in Cameroon |
| title_sort | evidence of exposure and human seroconversion during an outbreak of avian influenza a h5n1 among poultry in cameroon |
| topic | Avian influenza H5N1 Africa Cameroon Zoonoses surveillance |
| url | https://www.tandfonline.com/doi/10.1080/22221751.2018.1564631 |
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