Osteopontin Promotes Bone Destruction in Periapical Periodontitis by Activating the NF-κB Pathway

Osteopontin Promotes Bone Destruction in Periapical Periodontitis by Activating the NF-κB Pathway

Background/Aims: Periapical periodontitis is caused by bacterial infection and results in both one destruction and tooth loss. Osteopontin (OPN) is a secreted phosphorylated glycoprotein that participates in bone metabolism. Methods: Thirty-three patients with chronic periapical periodontitis and 10...

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Bibliographic Details
Main Authors: Ming Dong, Xinxin Yu, Wanfang Chen, Zhenzhen Guo, Linlin Sui, Yuefei Xu, Yuhong Shang, Weidong Niu, Ying Kong
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-09-01
Series:Cellular Physiology and Biochemistry
Subjects:
Osteopontin
Bone absorption
Periapical periodontitis
NF-κB
Online Access:https://www.karger.com/Article/FullText/493219

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