Beclin1 controls caspase-4 inflammsome activation and pyroptosis in mouse myocardial reperfusion-induced microvascular injury

Beclin1 controls caspase-4 inflammsome activation and pyroptosis in mouse myocardial reperfusion-induced microvascular injury

Abstract Background Myocardial reperfusion injury is often accompanied by cell death and inflammatory reactions. Recently, pyroptosis is gradually recognized as pivotal role in cardiovascular disease. However, little is known about the regulatory role of beclin1 in the control of caspase-4 activatio...

Full description

Bibliographic Details
Main Authors: Wenjing Sun, Hongquan Lu, Shujuan Dong, Rui Li, Yingjie Chu, Nan Wang, Yu Zhao, Yabin Zhang, Limeiting Wang, Lin Sun, Di Lu
Format: Article
Language:English
Published: BMC 2021-11-01
Series:Cell Communication and Signaling
Subjects:
Ischemia/reperfusion
Caspase-4 inflammasome
Pyroptosis
Beclin1
Online Access:https://doi.org/10.1186/s12964-021-00786-z

Similar Items

Similar Items