Divergence in the activity of the N- and C- catalytic domains of ACE1 - implications for the role of the renin-angiotensin system in Alzheimer’s disease
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2019-04-01
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| Series: | Acta Neuropathologica Communications |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s40478-019-0718-2 |
| _version_ | 1818842342288785408 |
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| author | Noura S. AL Mulhim Patrick G. Kehoe J. Scott Miners |
| author_facet | Noura S. AL Mulhim Patrick G. Kehoe J. Scott Miners |
| author_sort | Noura S. AL Mulhim |
| collection | DOAJ |
| first_indexed | 2024-12-19T04:40:27Z |
| format | Article |
| id | doaj.art-766bb8bdfde841e882a5fbe270001e50 |
| institution | Directory Open Access Journal |
| issn | 2051-5960 |
| language | English |
| last_indexed | 2024-12-19T04:40:27Z |
| publishDate | 2019-04-01 |
| publisher | BMC |
| record_format | Article |
| series | Acta Neuropathologica Communications |
| spelling | doaj.art-766bb8bdfde841e882a5fbe270001e502022-12-21T20:35:38ZengBMCActa Neuropathologica Communications2051-59602019-04-01711310.1186/s40478-019-0718-2Divergence in the activity of the N- and C- catalytic domains of ACE1 - implications for the role of the renin-angiotensin system in Alzheimer’s diseaseNoura S. AL Mulhim0Patrick G. Kehoe1J. Scott Miners2Dementia Research Group, Translational Health Sciences, Bristol Medical School, University of Bristol, Level 1 Learning and Research, Southmead HospitalDementia Research Group, Translational Health Sciences, Bristol Medical School, University of Bristol, Level 1 Learning and Research, Southmead HospitalDementia Research Group, Translational Health Sciences, Bristol Medical School, University of Bristol, Level 1 Learning and Research, Southmead Hospitalhttp://link.springer.com/article/10.1186/s40478-019-0718-2Angiotensin-II converting enzyme-1 (ACE1)Alzheimer’s diseaseRenin-angiotensin systemAnti-hypertensives |
| spellingShingle | Noura S. AL Mulhim Patrick G. Kehoe J. Scott Miners Divergence in the activity of the N- and C- catalytic domains of ACE1 - implications for the role of the renin-angiotensin system in Alzheimer’s disease Acta Neuropathologica Communications Angiotensin-II converting enzyme-1 (ACE1) Alzheimer’s disease Renin-angiotensin system Anti-hypertensives |
| title | Divergence in the activity of the N- and C- catalytic domains of ACE1 - implications for the role of the renin-angiotensin system in Alzheimer’s disease |
| title_full | Divergence in the activity of the N- and C- catalytic domains of ACE1 - implications for the role of the renin-angiotensin system in Alzheimer’s disease |
| title_fullStr | Divergence in the activity of the N- and C- catalytic domains of ACE1 - implications for the role of the renin-angiotensin system in Alzheimer’s disease |
| title_full_unstemmed | Divergence in the activity of the N- and C- catalytic domains of ACE1 - implications for the role of the renin-angiotensin system in Alzheimer’s disease |
| title_short | Divergence in the activity of the N- and C- catalytic domains of ACE1 - implications for the role of the renin-angiotensin system in Alzheimer’s disease |
| title_sort | divergence in the activity of the n and c catalytic domains of ace1 implications for the role of the renin angiotensin system in alzheimer s disease |
| topic | Angiotensin-II converting enzyme-1 (ACE1) Alzheimer’s disease Renin-angiotensin system Anti-hypertensives |
| url | http://link.springer.com/article/10.1186/s40478-019-0718-2 |
| work_keys_str_mv | AT nourasalmulhim divergenceintheactivityofthenandccatalyticdomainsoface1implicationsfortheroleofthereninangiotensinsysteminalzheimersdisease AT patrickgkehoe divergenceintheactivityofthenandccatalyticdomainsoface1implicationsfortheroleofthereninangiotensinsysteminalzheimersdisease AT jscottminers divergenceintheactivityofthenandccatalyticdomainsoface1implicationsfortheroleofthereninangiotensinsysteminalzheimersdisease |