Percutaneous Left Atrial Appendage Occlusion: What the Practising Physician Should Know

Non-valvular AF is a common clinical condition associated with an increased risk of thromboembolic complications. As a consequence, oral anticoagulant therapy (OAT) is the cornerstone of non-valvular AF management. Despite the well-established efficacy of OAT, many patients cannot receive this preve...

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Bibliographic Details
Main Authors: Pierluigi Merella, Giuseppe Talanas, Giovanni Lorenzoni, Cristiana Denurra, Enrico Atzori, Gavino Casu
Format: Article
Language:English
Published: Radcliffe Medical Media 2023-09-01
Series:European Cardiology Review
Online Access:https://www.ecrjournal.com/articleindex/ecr.2023.18
Description
Summary:Non-valvular AF is a common clinical condition associated with an increased risk of thromboembolic complications. As a consequence, oral anticoagulant therapy (OAT) is the cornerstone of non-valvular AF management. Despite the well-established efficacy of OAT, many patients cannot receive this preventive therapy due to bleeding or a high risk of bleeding. The fact that more than 90% of thrombi are formed in the left atrial appendage has led to the development of alternative methods to reduce the embolic risk. Left atrial appendage occlusion (LAAO) is a non-pharmacological option for preventing cardioembolic events in patients with non-valvular AF with a contraindication to OAT. The demand for LAAO procedures is growing exponentially and clinicians should consider this alternative option when managing patients with a contraindication to OAT. This review summarises the current thinking about LAAO.
ISSN:1758-3756
1758-3764