Percutaneous Left Atrial Appendage Occlusion: What the Practising Physician Should Know

Non-valvular AF is a common clinical condition associated with an increased risk of thromboembolic complications. As a consequence, oral anticoagulant therapy (OAT) is the cornerstone of non-valvular AF management. Despite the well-established efficacy of OAT, many patients cannot receive this preve...

Full description

Bibliographic Details
Main Authors: Pierluigi Merella, Giuseppe Talanas, Giovanni Lorenzoni, Cristiana Denurra, Enrico Atzori, Gavino Casu
Format: Article
Language:English
Published: Radcliffe Medical Media 2023-09-01
Series:European Cardiology Review
Online Access:https://www.ecrjournal.com/articleindex/ecr.2023.18
_version_ 1826933134027915264
author Pierluigi Merella
Giuseppe Talanas
Giovanni Lorenzoni
Cristiana Denurra
Enrico Atzori
Gavino Casu
author_facet Pierluigi Merella
Giuseppe Talanas
Giovanni Lorenzoni
Cristiana Denurra
Enrico Atzori
Gavino Casu
author_sort Pierluigi Merella
collection DOAJ
description Non-valvular AF is a common clinical condition associated with an increased risk of thromboembolic complications. As a consequence, oral anticoagulant therapy (OAT) is the cornerstone of non-valvular AF management. Despite the well-established efficacy of OAT, many patients cannot receive this preventive therapy due to bleeding or a high risk of bleeding. The fact that more than 90% of thrombi are formed in the left atrial appendage has led to the development of alternative methods to reduce the embolic risk. Left atrial appendage occlusion (LAAO) is a non-pharmacological option for preventing cardioembolic events in patients with non-valvular AF with a contraindication to OAT. The demand for LAAO procedures is growing exponentially and clinicians should consider this alternative option when managing patients with a contraindication to OAT. This review summarises the current thinking about LAAO.
first_indexed 2024-03-07T17:39:03Z
format Article
id doaj.art-766d749ed896474594152712dcf945b3
institution Directory Open Access Journal
issn 1758-3756
1758-3764
language English
last_indexed 2025-02-17T17:27:11Z
publishDate 2023-09-01
publisher Radcliffe Medical Media
record_format Article
series European Cardiology Review
spelling doaj.art-766d749ed896474594152712dcf945b32024-12-14T16:04:42ZengRadcliffe Medical MediaEuropean Cardiology Review1758-37561758-37642023-09-011810.15420/ecr.2023.18Percutaneous Left Atrial Appendage Occlusion: What the Practising Physician Should KnowPierluigi Merella0Giuseppe Talanas1Giovanni Lorenzoni2Cristiana Denurra3Enrico Atzori4Gavino Casu5Department of Cardiology, Azienda Ospedaliero Universitaria di Sassari, Sassari, ItalyDepartment of Cardiology, Azienda Ospedaliero Universitaria di Sassari, Sassari, ItalyDepartment of Cardiology, Azienda Ospedaliero Universitaria di Sassari, Sassari, ItalyDepartment of Cardiology, Azienda Ospedaliero Universitaria di Sassari, Sassari, ItalyDepartment of Cardiology, Azienda Ospedaliero Universitaria di Sassari, Sassari, ItalyDepartment of Cardiology, Azienda Ospedaliero Universitaria di Sassari, Sassari, ItalyNon-valvular AF is a common clinical condition associated with an increased risk of thromboembolic complications. As a consequence, oral anticoagulant therapy (OAT) is the cornerstone of non-valvular AF management. Despite the well-established efficacy of OAT, many patients cannot receive this preventive therapy due to bleeding or a high risk of bleeding. The fact that more than 90% of thrombi are formed in the left atrial appendage has led to the development of alternative methods to reduce the embolic risk. Left atrial appendage occlusion (LAAO) is a non-pharmacological option for preventing cardioembolic events in patients with non-valvular AF with a contraindication to OAT. The demand for LAAO procedures is growing exponentially and clinicians should consider this alternative option when managing patients with a contraindication to OAT. This review summarises the current thinking about LAAO.https://www.ecrjournal.com/articleindex/ecr.2023.18
spellingShingle Pierluigi Merella
Giuseppe Talanas
Giovanni Lorenzoni
Cristiana Denurra
Enrico Atzori
Gavino Casu
Percutaneous Left Atrial Appendage Occlusion: What the Practising Physician Should Know
European Cardiology Review
title Percutaneous Left Atrial Appendage Occlusion: What the Practising Physician Should Know
title_full Percutaneous Left Atrial Appendage Occlusion: What the Practising Physician Should Know
title_fullStr Percutaneous Left Atrial Appendage Occlusion: What the Practising Physician Should Know
title_full_unstemmed Percutaneous Left Atrial Appendage Occlusion: What the Practising Physician Should Know
title_short Percutaneous Left Atrial Appendage Occlusion: What the Practising Physician Should Know
title_sort percutaneous left atrial appendage occlusion what the practising physician should know
url https://www.ecrjournal.com/articleindex/ecr.2023.18
work_keys_str_mv AT pierluigimerella percutaneousleftatrialappendageocclusionwhatthepractisingphysicianshouldknow
AT giuseppetalanas percutaneousleftatrialappendageocclusionwhatthepractisingphysicianshouldknow
AT giovannilorenzoni percutaneousleftatrialappendageocclusionwhatthepractisingphysicianshouldknow
AT cristianadenurra percutaneousleftatrialappendageocclusionwhatthepractisingphysicianshouldknow
AT enricoatzori percutaneousleftatrialappendageocclusionwhatthepractisingphysicianshouldknow
AT gavinocasu percutaneousleftatrialappendageocclusionwhatthepractisingphysicianshouldknow