Apocrine Hidrocystoma with IgG4 Plasma Cell Infiltration Presenting as Recurrent Chalazion: A Case Report
Apocrine hidrocystomas are benign cystic tumors resulting from apocrine sweat glands’ proliferation. They typically present as solitary, slow-growing nodules at the head and neck, especially in the periorbital cutaneous region. We present a case of periorbital apocrine hidrocystoma in a 22-year-old...
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MDPI AG
2022-06-01
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| Series: | Medicina |
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| Online Access: | https://www.mdpi.com/1648-9144/58/7/840 |
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| author | Shang-Yen Wu Jin-Wei Huang Yuan-Chieh Lee Fang-Ling Chang Ming-Hsun Li Nancy Chen |
| author_facet | Shang-Yen Wu Jin-Wei Huang Yuan-Chieh Lee Fang-Ling Chang Ming-Hsun Li Nancy Chen |
| author_sort | Shang-Yen Wu |
| collection | DOAJ |
| description | Apocrine hidrocystomas are benign cystic tumors resulting from apocrine sweat glands’ proliferation. They typically present as solitary, slow-growing nodules at the head and neck, especially in the periorbital cutaneous region. We present a case of periorbital apocrine hidrocystoma in a 22-year-old woman that was treated as chalazion previously. Besides the hallmark histopathological findings of apocrine hidrocystoma, IgG4 plasma cell infiltration of the cystic wall was also found. The ratio of IgG4-to-IgG-positive plasma cells was high, whereas serum IgG4 was within the standard limit. This is, to date, the only probable IgG4-related ophthalmic disease associated with apocrine hidrocystoma. |
| first_indexed | 2024-03-09T13:25:23Z |
| format | Article |
| id | doaj.art-766d7aef2bd444128c74d75e7ddd1ed4 |
| institution | Directory Open Access Journal |
| issn | 1010-660X 1648-9144 |
| language | English |
| last_indexed | 2024-03-09T13:25:23Z |
| publishDate | 2022-06-01 |
| publisher | MDPI AG |
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| series | Medicina |
| spelling | doaj.art-766d7aef2bd444128c74d75e7ddd1ed42023-11-30T21:24:40ZengMDPI AGMedicina1010-660X1648-91442022-06-0158784010.3390/medicina58070840Apocrine Hidrocystoma with IgG4 Plasma Cell Infiltration Presenting as Recurrent Chalazion: A Case ReportShang-Yen Wu0Jin-Wei Huang1Yuan-Chieh Lee2Fang-Ling Chang3Ming-Hsun Li4Nancy Chen5Department of Ophthalmology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien 970, TaiwanDepartment of Ophthalmology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien 970, TaiwanDepartment of Ophthalmology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien 970, TaiwanDepartment of Ophthalmology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien 970, TaiwanDepartment of Pathology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien 970, TaiwanDepartment of Ophthalmology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien 970, TaiwanApocrine hidrocystomas are benign cystic tumors resulting from apocrine sweat glands’ proliferation. They typically present as solitary, slow-growing nodules at the head and neck, especially in the periorbital cutaneous region. We present a case of periorbital apocrine hidrocystoma in a 22-year-old woman that was treated as chalazion previously. Besides the hallmark histopathological findings of apocrine hidrocystoma, IgG4 plasma cell infiltration of the cystic wall was also found. The ratio of IgG4-to-IgG-positive plasma cells was high, whereas serum IgG4 was within the standard limit. This is, to date, the only probable IgG4-related ophthalmic disease associated with apocrine hidrocystoma.https://www.mdpi.com/1648-9144/58/7/840apocrine hidrocystomaIgG4 plasma cellchalazionperi-orbital |
| spellingShingle | Shang-Yen Wu Jin-Wei Huang Yuan-Chieh Lee Fang-Ling Chang Ming-Hsun Li Nancy Chen Apocrine Hidrocystoma with IgG4 Plasma Cell Infiltration Presenting as Recurrent Chalazion: A Case Report Medicina apocrine hidrocystoma IgG4 plasma cell chalazion peri-orbital |
| title | Apocrine Hidrocystoma with IgG4 Plasma Cell Infiltration Presenting as Recurrent Chalazion: A Case Report |
| title_full | Apocrine Hidrocystoma with IgG4 Plasma Cell Infiltration Presenting as Recurrent Chalazion: A Case Report |
| title_fullStr | Apocrine Hidrocystoma with IgG4 Plasma Cell Infiltration Presenting as Recurrent Chalazion: A Case Report |
| title_full_unstemmed | Apocrine Hidrocystoma with IgG4 Plasma Cell Infiltration Presenting as Recurrent Chalazion: A Case Report |
| title_short | Apocrine Hidrocystoma with IgG4 Plasma Cell Infiltration Presenting as Recurrent Chalazion: A Case Report |
| title_sort | apocrine hidrocystoma with igg4 plasma cell infiltration presenting as recurrent chalazion a case report |
| topic | apocrine hidrocystoma IgG4 plasma cell chalazion peri-orbital |
| url | https://www.mdpi.com/1648-9144/58/7/840 |
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