Factors Related with Spondylodiscitis in Patients with Brucellosis
Introduction: Brucellosis is a systemic infection involving many organs and tissues which may present with very different clinical manifestations. In this study, it was aimed to review the cases with the diagnosis of brucellar spondylodiscitis followed up in our center. Materyal and Methods: Cases...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Bilimsel Tip Yayinevi
2016-06-01
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| Series: | Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi |
| Subjects: | |
| Online Access: | http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2016-21-02-082-087.pdf |
| Summary: | Introduction: Brucellosis is a systemic infection involving many organs and tissues which may present with very different clinical
manifestations. In this study, it was aimed to review the cases with the diagnosis of brucellar spondylodiscitis followed up in our center.
Materyal and Methods: Cases with the diagnosis of brucellar spondylodiscitis followed up in our clinic from July 2007 to February 2016 were reviewed. Brucellosis diagnosis was established via microbiological culture confirmation and/or agglutination test positivity with a titer of 1/160 or higher. The diagnosis of spondylodiscitis was made with magnetic resonance imaging method. The data were collected by retrospective chart review.
Results: During the study period, 94 cases of brucellosis were followed (36 females, 58 males, mean age:47.7 ± 15.5 years).
Spondylodiscitis was detected in 16 (17%) patients. The mean age of this group was 58.4 ± 11.1 and it was detected to be significantly higher than patients without spondylodiscitis (mean age 45.5 ± 15.4 years) (p= 0.001). The most frequently involved vertebrae were the lower thoracic and lower lumbar vertebras. Age (p< 0.0001), fever (p= 0.037), backache (p< 0.0001) and weakness-fatigue (p= 0.012) were found statically significant factors for spondylodiscitis. At the end of logistic regression, age higher than 54.5 years was found to be an independent risk factor of the brucellar spondylodiscitis (OR= 9.12; %95 CI= 2.03-41.01; p= 0.004).
Conclusion: Brucellosis should be screened in cases with lower thoracic and lower lumbar spondylodiscitis. Age is higher in patients with brucellar spondylodiscitis than others and age > 54.5 years is an independent risk factor for brcsellar spondylodiscitis. |
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| ISSN: | 1300-932X 1300-932X |