Contributions of Titin and Collagen to Passive Stress in Muscles from <i>mdm</i> Mice with a Small Deletion in Titin’s Molecular Spring

Contributions of Titin and Collagen to Passive Stress in Muscles from <i>mdm</i> Mice with a Small Deletion in Titin’s Molecular Spring

Muscular dystrophy with myositis (<i>mdm</i>) is a naturally occurring mutation in the mouse <i>Ttn</i> gene that results in higher passive stress in muscle fibers and intact muscles compared to wild-type (WT). The goal of this study was to test whether alternative splicing o...

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Bibliographic Details
Main Authors: Pabodha Hettige, Dhruv Mishra, Henk Granzier, Kiisa Nishikawa, Matthew J. Gage
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
soleus
fiber bundles
trypsin
KCl
KI
exon splicing
Online Access:https://www.mdpi.com/1422-0067/23/16/8858

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