Photochemotherapy Induces Interferon Type III Expression via STING Pathway

Photochemotherapy Induces Interferon Type III Expression via STING Pathway

DNA-damaging cancer therapies induce interferon expression and stimulate the immune system, promoting therapy responses. The immune-activating STING (Stimulator of Interferon Genes) pathway is induced when DNA or double-stranded RNA (dsRNA) is detected in the cell cytoplasm, which can be caused by v...

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Bibliographic Details
Main Authors: Edyta Biskup, Brian Daniel Larsen, Leonor Rib, Lasse Folkersen, Omid Niazi, Maria R. Kamstrup, Claus Storgaard Sørensen
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Cells
Subjects:
DNA damage
STING
PUVA
CTCL
IFNL1
Online Access:https://www.mdpi.com/2073-4409/9/11/2452

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