Serosurvey of IgG Antibodies against <i>Bartonella henselae</i> and <i>Rickettsia typhi</i> in the Population of Attica, Greece
<i>Rickettsia typhi and Bartonella henselae</i> are the causative agents of murine typhus and cat-scratch disease, respectively. A small-scale survey (N = 202) was conducted in the Attica region, Greece, for determining the prevalence rates of IgG antibodies against <i>B. henselae&...
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MDPI AG
2020-09-01
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| Series: | Tropical Medicine and Infectious Disease |
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| Online Access: | https://www.mdpi.com/2414-6366/5/3/145 |
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| author | Georgios Dougas Maria Mavrouli Athanassios Tsakris Charalambos Billinis Joseph Papaparaskevas |
| author_facet | Georgios Dougas Maria Mavrouli Athanassios Tsakris Charalambos Billinis Joseph Papaparaskevas |
| author_sort | Georgios Dougas |
| collection | DOAJ |
| description | <i>Rickettsia typhi and Bartonella henselae</i> are the causative agents of murine typhus and cat-scratch disease, respectively. A small-scale survey (N = 202) was conducted in the Attica region, Greece, for determining the prevalence rates of IgG antibodies against <i>B. henselae</i> and <i>R. typhi</i> by indirect fluorescence antibody test. IgG against <i>B. henselae</i> and <i>R. typhi</i> were present in 17.8% (36/202) and 4.5% (9/202) of the participants, respectively; co-occurring IgG against both <i>B. henselae</i> and <i>R. typhi</i> were detected in 3.5% (7/202), whereas only anti-<i>B. henselae</i> IgG in 14.3% (29/202), and only anti-<i>R. typhi</i> IgG in 1.0% (2/202). Titres 1/64, 1/128, 1/256, and 1/512, of anti-<i>B. henselae</i> IgG were identified in 6.4%, 4.5%, 4.5%, and 2.4%, whereas titres 1/40 and 1/80 of anti-<i>R. typhi</i> IgG were detected in 4.0%, and 0.5%, respectively. A positive association of anti-<i>B. henselae</i> IgG prevalence with a coastal area featuring a major seaport (<i>p</i> = 0.009) and with younger age (<i>p</i> = 0.046) was identified. The findings of this survey raise concern for exposure of the population of Attica to <i>B. henselae</i> and <i>R. typhi</i>, which should be considered in the differential diagnosis when compatible symptoms are present. Our results also suggest that seaports may represent high-risk areas for exposure to <i>Bartonella</i> spp. |
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| spelling | doaj.art-7675f2cebe0b49d8ab82ec969723c7742023-11-20T13:52:35ZengMDPI AGTropical Medicine and Infectious Disease2414-63662020-09-015314510.3390/tropicalmed5030145Serosurvey of IgG Antibodies against <i>Bartonella henselae</i> and <i>Rickettsia typhi</i> in the Population of Attica, GreeceGeorgios Dougas0Maria Mavrouli1Athanassios Tsakris2Charalambos Billinis3Joseph Papaparaskevas4Department of Microbiology, Medical School, National and Kapodistrian University of Athens, 11527 Athens, GreeceDepartment of Microbiology, Medical School, National and Kapodistrian University of Athens, 11527 Athens, GreeceDepartment of Microbiology, Medical School, National and Kapodistrian University of Athens, 11527 Athens, GreeceDepartment of Microbiology and Parasitology, Faculty of Veterinary Science, University of Thessaly, 43100 Karditsa, GreeceDepartment of Microbiology, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece<i>Rickettsia typhi and Bartonella henselae</i> are the causative agents of murine typhus and cat-scratch disease, respectively. A small-scale survey (N = 202) was conducted in the Attica region, Greece, for determining the prevalence rates of IgG antibodies against <i>B. henselae</i> and <i>R. typhi</i> by indirect fluorescence antibody test. IgG against <i>B. henselae</i> and <i>R. typhi</i> were present in 17.8% (36/202) and 4.5% (9/202) of the participants, respectively; co-occurring IgG against both <i>B. henselae</i> and <i>R. typhi</i> were detected in 3.5% (7/202), whereas only anti-<i>B. henselae</i> IgG in 14.3% (29/202), and only anti-<i>R. typhi</i> IgG in 1.0% (2/202). Titres 1/64, 1/128, 1/256, and 1/512, of anti-<i>B. henselae</i> IgG were identified in 6.4%, 4.5%, 4.5%, and 2.4%, whereas titres 1/40 and 1/80 of anti-<i>R. typhi</i> IgG were detected in 4.0%, and 0.5%, respectively. A positive association of anti-<i>B. henselae</i> IgG prevalence with a coastal area featuring a major seaport (<i>p</i> = 0.009) and with younger age (<i>p</i> = 0.046) was identified. The findings of this survey raise concern for exposure of the population of Attica to <i>B. henselae</i> and <i>R. typhi</i>, which should be considered in the differential diagnosis when compatible symptoms are present. Our results also suggest that seaports may represent high-risk areas for exposure to <i>Bartonella</i> spp.https://www.mdpi.com/2414-6366/5/3/145seroepidemiologic studiesserology<i>Bartonella henselae</i><i>Rickettsia typhi</i>fluorescent antibody techniquerats |
| spellingShingle | Georgios Dougas Maria Mavrouli Athanassios Tsakris Charalambos Billinis Joseph Papaparaskevas Serosurvey of IgG Antibodies against <i>Bartonella henselae</i> and <i>Rickettsia typhi</i> in the Population of Attica, Greece Tropical Medicine and Infectious Disease seroepidemiologic studies serology <i>Bartonella henselae</i> <i>Rickettsia typhi</i> fluorescent antibody technique rats |
| title | Serosurvey of IgG Antibodies against <i>Bartonella henselae</i> and <i>Rickettsia typhi</i> in the Population of Attica, Greece |
| title_full | Serosurvey of IgG Antibodies against <i>Bartonella henselae</i> and <i>Rickettsia typhi</i> in the Population of Attica, Greece |
| title_fullStr | Serosurvey of IgG Antibodies against <i>Bartonella henselae</i> and <i>Rickettsia typhi</i> in the Population of Attica, Greece |
| title_full_unstemmed | Serosurvey of IgG Antibodies against <i>Bartonella henselae</i> and <i>Rickettsia typhi</i> in the Population of Attica, Greece |
| title_short | Serosurvey of IgG Antibodies against <i>Bartonella henselae</i> and <i>Rickettsia typhi</i> in the Population of Attica, Greece |
| title_sort | serosurvey of igg antibodies against i bartonella henselae i and i rickettsia typhi i in the population of attica greece |
| topic | seroepidemiologic studies serology <i>Bartonella henselae</i> <i>Rickettsia typhi</i> fluorescent antibody technique rats |
| url | https://www.mdpi.com/2414-6366/5/3/145 |
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