Distinct differences in the expansion and phenotype of TB10.4 specific CD8 and CD4 T cells after infection with Mycobacterium tuberculosis.
BACKGROUND: Recently we and others have identified CD8 and CD4 T cell epitopes within the highly expressed M. tuberculosis protein TB10.4. This has enabled, for the first time, a comparative study of the dynamics and function of CD4 and CD8 T cells specific for epitopes within the same protein in va...
Main Authors: | Truc Thi Kim Thanh Hoang, Anneline Nansen, Sugata Roy, Rolf Billeskov, Claus Aagaard, Tara Elvang, Jes Dietrich, Peter Andersen |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2691482?pdf=render |
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