Investigation of the Risk Factors and Associated Co-Morbid Conditions among Patients with Colorectal Cancer in Trinidad
Colorectal cancer (CRC) is the third most common cancer, and the fourth most common cause of cancer mortality worldwide. In Trinidad and Tobago, it is the third most common type of cancer in both sexes. Since there is scanty research on the risk factors associated with CRC, this study was conducted...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-07-01
|
| Series: | Gastrointestinal Disorders |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2624-5647/2/3/20 |
| _version_ | 1827713191482753024 |
|---|---|
| author | Vijay Kumar Chattu Priya Gopie Rajiv K. Singh Kimberly Singh Sachin Singh Sarah Singh Javanna Smith Vitra Sookram DeAngello Saunders Krissi Thomas |
| author_facet | Vijay Kumar Chattu Priya Gopie Rajiv K. Singh Kimberly Singh Sachin Singh Sarah Singh Javanna Smith Vitra Sookram DeAngello Saunders Krissi Thomas |
| author_sort | Vijay Kumar Chattu |
| collection | DOAJ |
| description | Colorectal cancer (CRC) is the third most common cancer, and the fourth most common cause of cancer mortality worldwide. In Trinidad and Tobago, it is the third most common type of cancer in both sexes. Since there is scanty research on the risk factors associated with CRC, this study was conducted to determine the correlation between risk factors, including associated comorbid conditions, and CRC in Trinidad. A cross-sectional study was conducted amongst diagnosed CRC patients (>18 years) using a pre-tested questionnaire consisting of sections on demographic data, lifestyle before diagnosis, quality of life, and depression status. Additional information such as recurrence of cancer, Body Mass Index (BMI), Hypertension (HT), blood glucose levels and family history of cancer were collected from the medical records. Of the total participants, the majority were males (58%), and the mean age of diagnosis in both sexes was 65 years. The retrospective chart review showed that 68% were found to have a comorbid condition (Diabetes or HT). Upon review of the medical records, 93.2% of the subjects did not have a familial history. However, the questionnaire data showed that 73% of subjects had a family history. Around 50% of CRC patients were alcohol consumers and 30% were cigarette smokers prior to their cancer diagnosis. Interestingly, a majority of patients (91%) had never been screened for CRC prior to their diagnosis. Subjects with CRC displayed minimal depression, indicating that being diagnosed with CRC did not have a grave impact on their state of mind or quality of life. Our findings showed that prevalence of CRC was higher in males and amongst individuals of African descent. However, larger prospective studies may be warranted to fully demonstrate this effect. |
| first_indexed | 2024-03-10T18:30:38Z |
| format | Article |
| id | doaj.art-76783329c59345ff9ef5c1288275a798 |
| institution | Directory Open Access Journal |
| issn | 2624-5647 |
| language | English |
| last_indexed | 2024-03-10T18:30:38Z |
| publishDate | 2020-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Gastrointestinal Disorders |
| spelling | doaj.art-76783329c59345ff9ef5c1288275a7982023-11-20T06:40:53ZengMDPI AGGastrointestinal Disorders2624-56472020-07-012319320110.3390/gidisord2030020Investigation of the Risk Factors and Associated Co-Morbid Conditions among Patients with Colorectal Cancer in TrinidadVijay Kumar Chattu0Priya Gopie1Rajiv K. Singh2Kimberly Singh3Sachin Singh4Sarah Singh5Javanna Smith6Vitra Sookram7DeAngello Saunders8Krissi Thomas9Department of Medicine, Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, CanadaDepartment of Haematology/Oncology, Sangre Grande Hospital, Eastern Regional Health Authority, Sangre Grande, Trinidad and TobagoDepartment of Clinical Medical Sciences, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad and TobagoDepartment of Clinical Medical Sciences, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad and TobagoDepartment of Clinical Medical Sciences, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad and TobagoDepartment of Clinical Medical Sciences, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad and TobagoDepartment of Clinical Medical Sciences, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad and TobagoDepartment of Clinical Medical Sciences, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad and TobagoDepartment of Clinical Medical Sciences, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad and TobagoDepartment of Clinical Medical Sciences, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad and TobagoColorectal cancer (CRC) is the third most common cancer, and the fourth most common cause of cancer mortality worldwide. In Trinidad and Tobago, it is the third most common type of cancer in both sexes. Since there is scanty research on the risk factors associated with CRC, this study was conducted to determine the correlation between risk factors, including associated comorbid conditions, and CRC in Trinidad. A cross-sectional study was conducted amongst diagnosed CRC patients (>18 years) using a pre-tested questionnaire consisting of sections on demographic data, lifestyle before diagnosis, quality of life, and depression status. Additional information such as recurrence of cancer, Body Mass Index (BMI), Hypertension (HT), blood glucose levels and family history of cancer were collected from the medical records. Of the total participants, the majority were males (58%), and the mean age of diagnosis in both sexes was 65 years. The retrospective chart review showed that 68% were found to have a comorbid condition (Diabetes or HT). Upon review of the medical records, 93.2% of the subjects did not have a familial history. However, the questionnaire data showed that 73% of subjects had a family history. Around 50% of CRC patients were alcohol consumers and 30% were cigarette smokers prior to their cancer diagnosis. Interestingly, a majority of patients (91%) had never been screened for CRC prior to their diagnosis. Subjects with CRC displayed minimal depression, indicating that being diagnosed with CRC did not have a grave impact on their state of mind or quality of life. Our findings showed that prevalence of CRC was higher in males and amongst individuals of African descent. However, larger prospective studies may be warranted to fully demonstrate this effect.https://www.mdpi.com/2624-5647/2/3/20colorectal cancerhypertensiondiabetes mellitusdepressionquality of lifeTrinidad and Tobago |
| spellingShingle | Vijay Kumar Chattu Priya Gopie Rajiv K. Singh Kimberly Singh Sachin Singh Sarah Singh Javanna Smith Vitra Sookram DeAngello Saunders Krissi Thomas Investigation of the Risk Factors and Associated Co-Morbid Conditions among Patients with Colorectal Cancer in Trinidad Gastrointestinal Disorders colorectal cancer hypertension diabetes mellitus depression quality of life Trinidad and Tobago |
| title | Investigation of the Risk Factors and Associated Co-Morbid Conditions among Patients with Colorectal Cancer in Trinidad |
| title_full | Investigation of the Risk Factors and Associated Co-Morbid Conditions among Patients with Colorectal Cancer in Trinidad |
| title_fullStr | Investigation of the Risk Factors and Associated Co-Morbid Conditions among Patients with Colorectal Cancer in Trinidad |
| title_full_unstemmed | Investigation of the Risk Factors and Associated Co-Morbid Conditions among Patients with Colorectal Cancer in Trinidad |
| title_short | Investigation of the Risk Factors and Associated Co-Morbid Conditions among Patients with Colorectal Cancer in Trinidad |
| title_sort | investigation of the risk factors and associated co morbid conditions among patients with colorectal cancer in trinidad |
| topic | colorectal cancer hypertension diabetes mellitus depression quality of life Trinidad and Tobago |
| url | https://www.mdpi.com/2624-5647/2/3/20 |
| work_keys_str_mv | AT vijaykumarchattu investigationoftheriskfactorsandassociatedcomorbidconditionsamongpatientswithcolorectalcancerintrinidad AT priyagopie investigationoftheriskfactorsandassociatedcomorbidconditionsamongpatientswithcolorectalcancerintrinidad AT rajivksingh investigationoftheriskfactorsandassociatedcomorbidconditionsamongpatientswithcolorectalcancerintrinidad AT kimberlysingh investigationoftheriskfactorsandassociatedcomorbidconditionsamongpatientswithcolorectalcancerintrinidad AT sachinsingh investigationoftheriskfactorsandassociatedcomorbidconditionsamongpatientswithcolorectalcancerintrinidad AT sarahsingh investigationoftheriskfactorsandassociatedcomorbidconditionsamongpatientswithcolorectalcancerintrinidad AT javannasmith investigationoftheriskfactorsandassociatedcomorbidconditionsamongpatientswithcolorectalcancerintrinidad AT vitrasookram investigationoftheriskfactorsandassociatedcomorbidconditionsamongpatientswithcolorectalcancerintrinidad AT deangellosaunders investigationoftheriskfactorsandassociatedcomorbidconditionsamongpatientswithcolorectalcancerintrinidad AT krissithomas investigationoftheriskfactorsandassociatedcomorbidconditionsamongpatientswithcolorectalcancerintrinidad |