Microemulsion Based Nanostructures for Drug Delivery
Most of the active pharmaceutical compounds are often prone to display low bioavailability and biological degradation represents an important drawback. Due to the above, the development of a drug delivery system (DDS) that enables the introduction of a pharmaceutical compound through the body to ach...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-01-01
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| Series: | Frontiers in Nanotechnology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnano.2021.753947/full |
| _version_ | 1798035644676571136 |
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| author | Teresita Arredondo-Ochoa Teresita Arredondo-Ochoa Guillermo A. Silva-Martínez Guillermo A. Silva-Martínez |
| author_facet | Teresita Arredondo-Ochoa Teresita Arredondo-Ochoa Guillermo A. Silva-Martínez Guillermo A. Silva-Martínez |
| author_sort | Teresita Arredondo-Ochoa |
| collection | DOAJ |
| description | Most of the active pharmaceutical compounds are often prone to display low bioavailability and biological degradation represents an important drawback. Due to the above, the development of a drug delivery system (DDS) that enables the introduction of a pharmaceutical compound through the body to achieve a therapeutic effect in a controlled manner is an expanding application. Henceforth, new strategies have been developed to control several parameters considered essential for enhancing delivery of drugs. Nanostructure synthesis by microemulsions (ME) consist of enclosing a substance within a wall material at the nanoscale level, allowing to control the size and surface area of the resulting particle. This nanotechnology has shown the importance on targeted drug delivery to improve their stability by protecting a bioactive compound from an adverse environment, enhanced bioavailability as well as controlled release. Thus, a lower dose administration could be achieved by minimizing systemic side effects and decreasing toxicity. This review will focus on describing the different biocompatible nanostructures synthesized by ME as controlled DDS for therapeutic purposes. |
| first_indexed | 2024-04-11T21:01:07Z |
| format | Article |
| id | doaj.art-7678f77528ce4c6b852c81a31dcb0614 |
| institution | Directory Open Access Journal |
| issn | 2673-3013 |
| language | English |
| last_indexed | 2024-04-11T21:01:07Z |
| publishDate | 2022-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Nanotechnology |
| spelling | doaj.art-7678f77528ce4c6b852c81a31dcb06142022-12-22T04:03:30ZengFrontiers Media S.A.Frontiers in Nanotechnology2673-30132022-01-01310.3389/fnano.2021.753947753947Microemulsion Based Nanostructures for Drug DeliveryTeresita Arredondo-Ochoa0Teresita Arredondo-Ochoa1Guillermo A. Silva-Martínez2Guillermo A. Silva-Martínez3Laboratorio Especializado en Análisis de Alimentos, Facultad de Química, Universidad Autónoma de Querétaro, Querétaro, MexicoBio-Foods Research Lab, Tecnologico de Monterrey, Escuela de Ingeniería y Ciencias, Querétaro, MexicoLaboratorio de Biología Molecular, Departamento de Ingeniería Bioquímica, Tecnológico Nacional de México en Celaya, Celaya, MexicoCátedras CONACYT-TecNM en Celaya, Departamento de Ingeniería Bioquímica, Tecnológico Nacional de México en Celaya, Celaya, MexicoMost of the active pharmaceutical compounds are often prone to display low bioavailability and biological degradation represents an important drawback. Due to the above, the development of a drug delivery system (DDS) that enables the introduction of a pharmaceutical compound through the body to achieve a therapeutic effect in a controlled manner is an expanding application. Henceforth, new strategies have been developed to control several parameters considered essential for enhancing delivery of drugs. Nanostructure synthesis by microemulsions (ME) consist of enclosing a substance within a wall material at the nanoscale level, allowing to control the size and surface area of the resulting particle. This nanotechnology has shown the importance on targeted drug delivery to improve their stability by protecting a bioactive compound from an adverse environment, enhanced bioavailability as well as controlled release. Thus, a lower dose administration could be achieved by minimizing systemic side effects and decreasing toxicity. This review will focus on describing the different biocompatible nanostructures synthesized by ME as controlled DDS for therapeutic purposes.https://www.frontiersin.org/articles/10.3389/fnano.2021.753947/fullnanostructuresmicroemulsion (ME)drug delivery systems (DDS)emulsion synthesisbiocompatible materials |
| spellingShingle | Teresita Arredondo-Ochoa Teresita Arredondo-Ochoa Guillermo A. Silva-Martínez Guillermo A. Silva-Martínez Microemulsion Based Nanostructures for Drug Delivery Frontiers in Nanotechnology nanostructures microemulsion (ME) drug delivery systems (DDS) emulsion synthesis biocompatible materials |
| title | Microemulsion Based Nanostructures for Drug Delivery |
| title_full | Microemulsion Based Nanostructures for Drug Delivery |
| title_fullStr | Microemulsion Based Nanostructures for Drug Delivery |
| title_full_unstemmed | Microemulsion Based Nanostructures for Drug Delivery |
| title_short | Microemulsion Based Nanostructures for Drug Delivery |
| title_sort | microemulsion based nanostructures for drug delivery |
| topic | nanostructures microemulsion (ME) drug delivery systems (DDS) emulsion synthesis biocompatible materials |
| url | https://www.frontiersin.org/articles/10.3389/fnano.2021.753947/full |
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