Serum adiponectin levels in gestational diabetes mellitus
Introduction: Gestational diabetes mellitus (GDM) is defined as any degree of glucose intolerance with onset or first recognition during pregnancy.[1] Pregnancy is a unique situation in which there is a physiological temporary increase in insulin resistance (IR). The mechanisms responsible for the g...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2016-01-01
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| Series: | Indian Journal of Endocrinology and Metabolism |
| Subjects: | |
| Online Access: | http://www.ijem.in/article.asp?issn=2230-8210;year=2016;volume=20;issue=6;spage=752;epage=755;aulast=Bhograj |
| _version_ | 1818352092297822208 |
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| author | Abhijit Bhograj K M Suryanarayana Ashwini Nayak N S Murthy Mala Dharmalingam Pramila Kalra |
| author_facet | Abhijit Bhograj K M Suryanarayana Ashwini Nayak N S Murthy Mala Dharmalingam Pramila Kalra |
| author_sort | Abhijit Bhograj |
| collection | DOAJ |
| description | Introduction: Gestational diabetes mellitus (GDM) is defined as any degree of glucose intolerance with onset or first recognition during pregnancy.[1] Pregnancy is a unique situation in which there is a physiological temporary increase in insulin resistance (IR). The mechanisms responsible for the gestational-induced IR are not completely understood. The current study was undertaken to compare adiponectin levels during 24–28 weeks period of gestation in drug-naive newly diagnosed GDM women with a cohort of normoglycemic pregnant women. Subjects and Methods: A total of 47 pregnant women in the age group of 18–40 years were included in this cross-sectional study, of which 13 were GDM cases and 34 were normoglycemic controls. Serum adiponectin level was analyzed by enzyme-linked immunosorbent assay. Results: The mean adiponectin level was 16.92 ng/ml (standard deviation [SD] = 2.78) and 19.38 ng/ml (SD = 2.71) in case and control groups, respectively, and the difference was found to be statistically significant (P = 0.008). Conclusion: Our study demonstrated decreased serum adiponectin levels in women with GDM when compared with age- and body mass index-matched euglycemic pregnant women. |
| first_indexed | 2024-12-13T18:48:08Z |
| format | Article |
| id | doaj.art-76794435b32e48ca93128d9f856270f8 |
| institution | Directory Open Access Journal |
| issn | 2230-8210 |
| language | English |
| last_indexed | 2024-12-13T18:48:08Z |
| publishDate | 2016-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Endocrinology and Metabolism |
| spelling | doaj.art-76794435b32e48ca93128d9f856270f82022-12-21T23:35:01ZengWolters Kluwer Medknow PublicationsIndian Journal of Endocrinology and Metabolism2230-82102016-01-0120675275510.4103/2230-8210.192909Serum adiponectin levels in gestational diabetes mellitusAbhijit BhograjK M SuryanarayanaAshwini NayakN S MurthyMala DharmalingamPramila KalraIntroduction: Gestational diabetes mellitus (GDM) is defined as any degree of glucose intolerance with onset or first recognition during pregnancy.[1] Pregnancy is a unique situation in which there is a physiological temporary increase in insulin resistance (IR). The mechanisms responsible for the gestational-induced IR are not completely understood. The current study was undertaken to compare adiponectin levels during 24–28 weeks period of gestation in drug-naive newly diagnosed GDM women with a cohort of normoglycemic pregnant women. Subjects and Methods: A total of 47 pregnant women in the age group of 18–40 years were included in this cross-sectional study, of which 13 were GDM cases and 34 were normoglycemic controls. Serum adiponectin level was analyzed by enzyme-linked immunosorbent assay. Results: The mean adiponectin level was 16.92 ng/ml (standard deviation [SD] = 2.78) and 19.38 ng/ml (SD = 2.71) in case and control groups, respectively, and the difference was found to be statistically significant (P = 0.008). Conclusion: Our study demonstrated decreased serum adiponectin levels in women with GDM when compared with age- and body mass index-matched euglycemic pregnant women.http://www.ijem.in/article.asp?issn=2230-8210;year=2016;volume=20;issue=6;spage=752;epage=755;aulast=BhograjAdiponectinantenatal screeninggestational diabetes mellitus |
| spellingShingle | Abhijit Bhograj K M Suryanarayana Ashwini Nayak N S Murthy Mala Dharmalingam Pramila Kalra Serum adiponectin levels in gestational diabetes mellitus Indian Journal of Endocrinology and Metabolism Adiponectin antenatal screening gestational diabetes mellitus |
| title | Serum adiponectin levels in gestational diabetes mellitus |
| title_full | Serum adiponectin levels in gestational diabetes mellitus |
| title_fullStr | Serum adiponectin levels in gestational diabetes mellitus |
| title_full_unstemmed | Serum adiponectin levels in gestational diabetes mellitus |
| title_short | Serum adiponectin levels in gestational diabetes mellitus |
| title_sort | serum adiponectin levels in gestational diabetes mellitus |
| topic | Adiponectin antenatal screening gestational diabetes mellitus |
| url | http://www.ijem.in/article.asp?issn=2230-8210;year=2016;volume=20;issue=6;spage=752;epage=755;aulast=Bhograj |
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