RNA interference for CFTR attenuates lung fluid absorption at birth in rats
<p>Abstract</p> <p>Background</p> <p>Small interfering RNA (siRNA) against αENaC (α-subunit of the epithelial Na channel) and CFTR (cystic fibrosis transmembrane conductance regulator) was used to explore ENaC and CTFR function in newborn rat lungs.</p> <p>M...
Main Authors: | Folkesson Hans G, Koshy Shyny, Li Tianbo |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2008-07-01
|
Series: | Respiratory Research |
Online Access: | http://respiratory-research.com/content/9/1/55 |
Similar Items
-
Stimulation of MAP kinase pathways after maternal IL-1β exposure induces fetal lung fluid absorption in guinea pigs
by: Carter Ethan P, et al.
Published: (2007-03-01) -
CFTR-rich ionocytes mediate chloride absorption across airway epithelia
by: Lei Lei, et al.
Published: (2023-10-01) -
The gut-lung axis in the CFTR modulator era
by: Florian Lussac-Sorton, et al.
Published: (2023-09-01) -
CFTR Modulator Therapy for Rare CFTR Mutants
by: Marco Mergiotti, et al.
Published: (2022-04-01) -
Passaging Primary Human Bronchial Epithelia Reduces CFTR-Mediated Fluid Transport and Alters mRNA Expression
by: Tongde Wu, et al.
Published: (2023-03-01)