Reengineering Tumor Microenvironment with Sequential Interleukin Delivery

Reengineering Tumor Microenvironment with Sequential Interleukin Delivery

Some cytokines can reengineer anti-tumor immunity to modify the tumor micro-environment. Interleukin-27 (IL-27) can partially reduce tumor growth in several animal models, including prostate cancer. We hypothesized that addition of IL-18, which can induce the proliferation of several immune effector...

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Bibliographic Details
Main Authors: Marxa L. Figueiredo, Rachel Letteri, Delphine Chan-Seng, Shreya Kumar, Cosette M. Rivera-Cruz, Todd S. Emrick
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Bioengineering
Subjects:
Interleukin-27
targeted IL-27pepL
Interleukin-18
prostate cancer
immune effector signatures
sonoporation
Online Access:https://www.mdpi.com/2306-5354/8/7/90

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