Design & construction of a tapered optical fiber sensor for the detection of streptavidin protein
This paper presents the fabrication process and operation of a bio-sensor based on tapered optical fiber by using optical spectrum shift in the presence of PBS buffer and dissolved streptavidin. The taper-fiber sensors are 18 and 24 μm in diameter and are fabricated by use of an oxy-butane torch. Th...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Isfahan University of Technology
2022-11-01
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Series: | Iranian Journal of Physics Research |
Subjects: | |
Online Access: | https://ijpr.iut.ac.ir/article_3304_d13cac5e864a4a56bb6ca08f0529b787.pdf |
Summary: | This paper presents the fabrication process and operation of a bio-sensor based on tapered optical fiber by using optical spectrum shift in the presence of PBS buffer and dissolved streptavidin. The taper-fiber sensors are 18 and 24 μm in diameter and are fabricated by use of an oxy-butane torch. The optical spectrum is obtained using a broadband light source and an optical spectrum analyzer (OSA) in a 40 nm wavelength range. The existence of streptavidin on the tapered fiber surface is confirmed. The experiments on PBS buffer have shown that, the output spectrum demonstrates a red-shift by adding the streptavidin. The maximum sensitivity obtained is 29000 nm/RIU. |
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ISSN: | 1682-6957 2345-3664 |