Design & construction of a tapered optical fiber sensor for the detection of streptavidin protein

This paper presents the fabrication process and operation of a bio-sensor based on tapered optical fiber by using optical spectrum shift in the presence of PBS buffer and dissolved streptavidin. The taper-fiber sensors are 18 and 24 μm in diameter and are fabricated by use of an oxy-butane torch. Th...

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Bibliographic Details
Main Authors: Bahareh Mazlum Dizaji, Mohammad Vahedi, Ali Maleki, Hossein Saghafifar
Format: Article
Language:English
Published: Isfahan University of Technology 2022-11-01
Series:Iranian Journal of Physics Research
Subjects:
Online Access:https://ijpr.iut.ac.ir/article_3304_d13cac5e864a4a56bb6ca08f0529b787.pdf
Description
Summary:This paper presents the fabrication process and operation of a bio-sensor based on tapered optical fiber by using optical spectrum shift in the presence of PBS buffer and dissolved streptavidin. The taper-fiber sensors are 18 and 24 μm in diameter and are fabricated by use of an oxy-butane torch. The optical spectrum is obtained using a broadband light source and an optical spectrum analyzer (OSA) in a 40 nm wavelength range. The existence of streptavidin on the tapered fiber surface is confirmed. The experiments on PBS buffer have shown that, the output spectrum demonstrates a red-shift by adding the streptavidin. The maximum sensitivity obtained is 29000 nm/RIU.
ISSN:1682-6957
2345-3664