Magnetic Resonance Spectroscopy in Diagnosis and Follow-Up of Gliomas: State-of-the-Art

Preoperative grade prediction is important in diagnostics of glioma. Even more important can be follow-up after chemotherapy and radiotherapy of high grade gliomas. In this review we provide an overview of MR-spectroscopy (MRS), technical aspects, and different clinical scenarios in the diagnostics...

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Main Authors: Malik Galijasevic, Ruth Steiger, Stephanie Mangesius, Julian Mangesius, Johannes Kerschbaumer, Christian Franz Freyschlag, Nadja Gruber, Tanja Janjic, Elke Ruth Gizewski, Astrid Ellen Grams
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/14/13/3197
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author Malik Galijasevic
Ruth Steiger
Stephanie Mangesius
Julian Mangesius
Johannes Kerschbaumer
Christian Franz Freyschlag
Nadja Gruber
Tanja Janjic
Elke Ruth Gizewski
Astrid Ellen Grams
author_facet Malik Galijasevic
Ruth Steiger
Stephanie Mangesius
Julian Mangesius
Johannes Kerschbaumer
Christian Franz Freyschlag
Nadja Gruber
Tanja Janjic
Elke Ruth Gizewski
Astrid Ellen Grams
author_sort Malik Galijasevic
collection DOAJ
description Preoperative grade prediction is important in diagnostics of glioma. Even more important can be follow-up after chemotherapy and radiotherapy of high grade gliomas. In this review we provide an overview of MR-spectroscopy (MRS), technical aspects, and different clinical scenarios in the diagnostics and follow-up of gliomas in pediatric and adult populations. Furthermore, we provide a recap of the current research utility and possible future strategies regarding proton- and phosphorous-MRS in glioma research.
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spelling doaj.art-76854a2ae7b94b51b8c14067bb52089d2023-11-23T19:46:01ZengMDPI AGCancers2072-66942022-06-011413319710.3390/cancers14133197Magnetic Resonance Spectroscopy in Diagnosis and Follow-Up of Gliomas: State-of-the-ArtMalik Galijasevic0Ruth Steiger1Stephanie Mangesius2Julian Mangesius3Johannes Kerschbaumer4Christian Franz Freyschlag5Nadja Gruber6Tanja Janjic7Elke Ruth Gizewski8Astrid Ellen Grams9Department of Neuroradiology, Medical University of Innsbruck, 6020 Innsbruck, AustriaDepartment of Neuroradiology, Medical University of Innsbruck, 6020 Innsbruck, AustriaDepartment of Neuroradiology, Medical University of Innsbruck, 6020 Innsbruck, AustriaDepartment of Radiation Oncology, Medical University of Innsbruck, 6020 Innsbruck, AustriaDepartment of Neurosurgery, Medical University of Innsbruck, 6020 Innsbruck, AustriaDepartment of Neurosurgery, Medical University of Innsbruck, 6020 Innsbruck, AustriaVASCage-Research Centre on Vascular Ageing and Stroke, 6020 Innsbruck, AustriaDepartment of Neuroradiology, Medical University of Innsbruck, 6020 Innsbruck, AustriaDepartment of Neuroradiology, Medical University of Innsbruck, 6020 Innsbruck, AustriaDepartment of Neuroradiology, Medical University of Innsbruck, 6020 Innsbruck, AustriaPreoperative grade prediction is important in diagnostics of glioma. Even more important can be follow-up after chemotherapy and radiotherapy of high grade gliomas. In this review we provide an overview of MR-spectroscopy (MRS), technical aspects, and different clinical scenarios in the diagnostics and follow-up of gliomas in pediatric and adult populations. Furthermore, we provide a recap of the current research utility and possible future strategies regarding proton- and phosphorous-MRS in glioma research.https://www.mdpi.com/2072-6694/14/13/3197magnetic resonance spectroscopygliomaimaging biomarkers
spellingShingle Malik Galijasevic
Ruth Steiger
Stephanie Mangesius
Julian Mangesius
Johannes Kerschbaumer
Christian Franz Freyschlag
Nadja Gruber
Tanja Janjic
Elke Ruth Gizewski
Astrid Ellen Grams
Magnetic Resonance Spectroscopy in Diagnosis and Follow-Up of Gliomas: State-of-the-Art
Cancers
magnetic resonance spectroscopy
glioma
imaging biomarkers
title Magnetic Resonance Spectroscopy in Diagnosis and Follow-Up of Gliomas: State-of-the-Art
title_full Magnetic Resonance Spectroscopy in Diagnosis and Follow-Up of Gliomas: State-of-the-Art
title_fullStr Magnetic Resonance Spectroscopy in Diagnosis and Follow-Up of Gliomas: State-of-the-Art
title_full_unstemmed Magnetic Resonance Spectroscopy in Diagnosis and Follow-Up of Gliomas: State-of-the-Art
title_short Magnetic Resonance Spectroscopy in Diagnosis and Follow-Up of Gliomas: State-of-the-Art
title_sort magnetic resonance spectroscopy in diagnosis and follow up of gliomas state of the art
topic magnetic resonance spectroscopy
glioma
imaging biomarkers
url https://www.mdpi.com/2072-6694/14/13/3197
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