Genome sequencing of evolved aspergilli populations reveals robust genomes, transversions in A. flavus, and sexual aberrancy in non-homologous end-joining mutants

Genome sequencing of evolved aspergilli populations reveals robust genomes, transversions in A. flavus, and sexual aberrancy in non-homologous end-joining mutants

Abstract Background Aspergillus spp. comprises a very diverse group of lower eukaryotes with a high relevance for industrial applications and clinical implications. These multinucleate species are often cultured for many generations in the laboratory, which can unknowingly propagate hidden genetic m...

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Bibliographic Details
Main Authors: Isidro Álvarez-Escribano, Christoph Sasse, Jin Woo Bok, Hyunsoo Na, Mojgan Amirebrahimi, Anna Lipzen, Wendy Schackwitz, Joel Martin, Kerrie Barry, Gabriel Gutiérrez, Sara Cea-Sánchez, Ana T. Marcos, Igor V. Grigoriev, Nancy P. Keller, Gerhard H. Braus, David Cánovas
Format: Article
Language:English
Published: BMC 2019-11-01
Series:BMC Biology
Subjects:
Aspergillus
Aflatoxin
Mutation accumulating lines
Genome stability
Non-homologous end-joining
ku70
Online Access:http://link.springer.com/article/10.1186/s12915-019-0702-0

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