Memory consolidation during sleep involves context reinstatement in humans
Summary: New memories are not quarantined from each other when first encoded; rather, they are interlinked with memories that were encoded in temporal proximity or that share semantic features. By selectively biasing memory processing during sleep, here we test whether context influences sleep conso...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-04-01
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| Series: | Cell Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S221112472300342X |
| _version_ | 1797852987581792256 |
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| author | Eitan Schechtman Julia Heilberg Ken A. Paller |
| author_facet | Eitan Schechtman Julia Heilberg Ken A. Paller |
| author_sort | Eitan Schechtman |
| collection | DOAJ |
| description | Summary: New memories are not quarantined from each other when first encoded; rather, they are interlinked with memories that were encoded in temporal proximity or that share semantic features. By selectively biasing memory processing during sleep, here we test whether context influences sleep consolidation. Participants first formed 18 idiosyncratic narratives, each linking four objects together. Before sleep, they also memorized an on-screen position for each object. During sleep, 12 object-specific sounds were unobtrusively presented, thereby cuing the corresponding spatial memories and impacting spatial recall as a function of initial memory strength. As hypothesized, we find that recall for non-cued objects contextually linked with cued objects also changed. Post-cue electrophysiological responses suggest that activity in the sigma band supports context reinstatement and predicts context-related memory benefits. Concurrently, context-specific electrophysiological activity patterns emerge during sleep. We conclude that reactivation of individual memories during sleep evokes reinstatement of their context, thereby impacting consolidation of associated knowledge. |
| first_indexed | 2024-04-09T19:42:08Z |
| format | Article |
| id | doaj.art-768713267ed2411ea25b80e2de3a47c2 |
| institution | Directory Open Access Journal |
| issn | 2211-1247 |
| language | English |
| last_indexed | 2024-04-09T19:42:08Z |
| publishDate | 2023-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Cell Reports |
| spelling | doaj.art-768713267ed2411ea25b80e2de3a47c22023-04-04T04:08:42ZengElsevierCell Reports2211-12472023-04-01424112331Memory consolidation during sleep involves context reinstatement in humansEitan Schechtman0Julia Heilberg1Ken A. Paller2Department of Psychology, Northwestern University, Evanston, IL 60208, USA; Department of Neurobiology and Behavior, University of California at Irvine, Irvine, CA 92697, USA; Center for Neurobiology of Learning and Memory, University of California at Irvine, Irvine, CA 92697, USA; Corresponding authorDepartment of Psychology, Northwestern University, Evanston, IL 60208, USADepartment of Psychology, Northwestern University, Evanston, IL 60208, USASummary: New memories are not quarantined from each other when first encoded; rather, they are interlinked with memories that were encoded in temporal proximity or that share semantic features. By selectively biasing memory processing during sleep, here we test whether context influences sleep consolidation. Participants first formed 18 idiosyncratic narratives, each linking four objects together. Before sleep, they also memorized an on-screen position for each object. During sleep, 12 object-specific sounds were unobtrusively presented, thereby cuing the corresponding spatial memories and impacting spatial recall as a function of initial memory strength. As hypothesized, we find that recall for non-cued objects contextually linked with cued objects also changed. Post-cue electrophysiological responses suggest that activity in the sigma band supports context reinstatement and predicts context-related memory benefits. Concurrently, context-specific electrophysiological activity patterns emerge during sleep. We conclude that reactivation of individual memories during sleep evokes reinstatement of their context, thereby impacting consolidation of associated knowledge.http://www.sciencedirect.com/science/article/pii/S221112472300342XCP: Neuroscience |
| spellingShingle | Eitan Schechtman Julia Heilberg Ken A. Paller Memory consolidation during sleep involves context reinstatement in humans Cell Reports CP: Neuroscience |
| title | Memory consolidation during sleep involves context reinstatement in humans |
| title_full | Memory consolidation during sleep involves context reinstatement in humans |
| title_fullStr | Memory consolidation during sleep involves context reinstatement in humans |
| title_full_unstemmed | Memory consolidation during sleep involves context reinstatement in humans |
| title_short | Memory consolidation during sleep involves context reinstatement in humans |
| title_sort | memory consolidation during sleep involves context reinstatement in humans |
| topic | CP: Neuroscience |
| url | http://www.sciencedirect.com/science/article/pii/S221112472300342X |
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